Michigan State vs North Carolina College Basketball Prediction, Odds, Picks, Best Bets for Nov. 27

The Michigan State Spartans (6-0) take a six-game win streak into a home matchup with the North Carolina Tar Heels (6-0), winners of six straight as well.

Before you place your bet on this matchup at FanDuel Sportsbook, here are the NCAA basketball odds and spreads you need to know.

Michigan State vs. North Carolina Game Info and Odds

• Game day: Thursday, November 27, 2025
• Game time: 4:30 p.m. ET
• TV channel: FOX
• Location: Cypress Lake, Florida
• Arena: Suncoast Credit Union Arena

To help you make an informed wager on Michigan State-North Carolina outing (in which Michigan State is a 1.5-point favorite and the over/under has been set at 152.5 points), below are a few betting insights and trends for Thursday's game.

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Michigan State vs. North Carolina: ATS Betting Stats and Trends

• Michigan State has covered three times in six chances against the spread this season.
• North Carolina has won four games against the spread this season, while failing to cover twice.
• The Spartans covered the spread in a lower percentage of their home games than away games last year. They covered 10 times in 16 games when playing at home, and they covered seven times in nine games when playing on the road.
• Against the spread, the Tar Heels performed better at home (7-8-0) than away (4-8-0) last season.

Michigan State vs. North Carolina: Moneyline Betting Stats

• Michigan State has yet to lose any of the four games it has been chosen as the moneyline favorite in this season.
• The Spartans have been a -120 moneyline favorite on four occasions this season and won every game.
• North Carolina has not been the moneyline underdog yet this season.
• The Tar Heels have never played a game this season with moneyline odds of +100 or longer.
• The moneyline set for this matchup implies Michigan State has a 54.5% chance of walking away with the win.

Michigan State vs. North Carolina Head-to-Head Comparison

• With 77.7 points scored per game and 67.1 points allowed last year, Michigan State was 78th in the nation offensively and 44th defensively.
• Michigan State was the 10th-best squad in the country in rebounds per game (36.7) and ranked 28th in rebounds conceded (28.2) last year.
• Last season Michigan State was 24th-best in the nation in assists with 16.5 per game.
• Michigan State was 135th in the country in turnovers per game (10.7) and 265th in turnovers forced (10.4) last season.
• North Carolina was 29th in the nation last year with 80.7 points per game. At the other end of the court, it ranked 261st with 74.7 points allowed per contest.
• With 33.2 boards per game, North Carolina was 105th in college basketball. It ceded 31.2 rebounds per contest, which ranked 182nd in college basketball.
• North Carolina ranked 93rd in the country with 14.7 dimes per contest.
• North Carolina averaged 10.5 turnovers per game (120th-ranked in college basketball) this season, while forcing 10.2 turnovers per contest (288th-ranked).

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