Mariners vs Padres Prediction, Odds, Moneyline, Spread & Over/Under for Aug. 25

Odds updated as of 3:12 p.m.

The MLB slate on Monday includes the Seattle Mariners taking on the San Diego Padres.

Before checking out the MLB betting lines on FanDuel Sportsbook, we've got you covered, in terms of the vital information about this game.

Mariners vs Padres Game Info

• Seattle Mariners (70-61) vs. San Diego Padres (74-57)
• Date: Monday, August 25, 2025
• Time: 9:40 p.m. ET
• Venue: T-Mobile Park -- Seattle, Washington
• Coverage: ROOT Sports NW and SDPA

Mariners vs Padres Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: SEA: (-126) | SD: (+108)
• Spread: SEA: -1.5 (+164) | SD: +1.5 (-200)
• Total: 8 -- Over: (-122) | Under: (-100)

Mariners vs Padres Probable Starting Pitchers

Probable Pitchers: Bryce Miller (Mariners) - 2-5, 5.87 ERA vs JP Sears (Padres) - 8-10, 4.94 ERA

This contest's pitching matchup is set, as the Mariners will send Bryce Miller (2-5) to the mound, while JP Sears (8-10) will get the nod for the Padres. Miller's team is 4-7-0 against the spread this season in his starts. Miller's team has a record of 2-4 this season when he starts and they are the favorite on the moneyline. When Sears starts, the Padres have gone 13-11-0 against the spread. The Padres are 5-11 in Sears' 16 starts this season that they were the moneyline underdog.

Mariners vs Padres Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Mariners win (54%)

Mariners vs Padres Moneyline

• The Mariners vs Padres moneyline has Seattle as a -126 favorite, while San Diego is a +108 underdog on the road.

Mariners vs Padres Spread

• The Mariners are 1.5-run home favorites on the runline against the Padres. The Mariners are +164 to cover, and the Padres are -200.

Mariners vs Padres Over/Under

• An over/under of 8 has been set for Mariners-Padres on Aug. 25, with the over being -122 and the under -100.

Bet on Seattle Mariners vs. San Diego Padres on FanDuel today!

Mariners vs Padres Betting Trends

• The Mariners have been chosen as favorites in 86 games this year and have walked away with the win 49 times (57%) in those games.
• Seattle has a record of 40-25 when favored by -126 or more this year.
• The Mariners and their opponents have hit the over in 66 of their 126 games with a total set by oddsmakers this season.
• The Mariners have posted a record of 53-73-0 against the spread this season.
• The Padres are 29-29 in games they were the underdog on the moneyline (winning 50% of those games).
• San Diego is 21-23 (winning 47.7% of its games) when it has played as a moneyline underdog of +108 or longer.
• In the 129 games oddsmakers have set an over/under for the Padres, they have combined with opponents to go over the total 55 times (55-71-3).
• The Padres have put together a 73-56-0 record ATS this season.

Mariners Player Leaders

• Cal Raleigh leads Seattle in total hits (119) this season while batting .247 with 68 extra-base hits. He has an on-base percentage of .353 and a slugging percentage of .593.
• He is 104th in batting average, 37th in on-base percentage, and third in slugging among all qualified hitters in the majors.
• Julio Rodriguez has an OPS of .772, fueled by an OBP of .313 and a team-best slugging percentage of .459 this season. He's batting .259.
• Among qualifying batters, he is 76th in batting average, 110th in on-base percentage and 55th in slugging percentage.
• Josh Naylor has collected 125 base hits, an OBP of .347 and a slugging percentage of .449 this season.
• Naylor has logged a hit or more in three games in a row. During his last five outings he is batting .188 with a double, a home run, a walk and three RBIs.
• Eugenio Suarez has 40 home runs, 98 RBI and a batting average of .236 this season.

Padres Player Leaders

• Manny Machado has 147 hits with a .480 slugging percentage, both team-best marks for the Padres. He's batting .292 and with an on-base percentage of .354.
• He is 14th in batting average, 33rd in on-base percentage and 33rd in slugging percentage among all qualifying hitters in MLB.
• Fernando Tatis Jr. has a .373 on-base percentage to pace his team. He has a batting average of .264 while slugging .429.
• He ranks 57th in batting average, 12th in on-base percentage and 80th in slugging percentage in the majors.
• Luis Arraez is hitting .285 with 28 doubles, four triples, six home runs and 26 walks.
• Xander Bogaerts has 29 doubles, 10 home runs and 48 walks while batting .260.

Mariners vs Padres Head to Head

• 5/18/2025: 6-1 SEA (Favorite: Padres, Spread: -1.5, Total: 7.5, Favorite Moneyline: -142, Underdog Moneyline: +120)
• 5/17/2025: 4-1 SEA (Favorite: Padres, Spread: -1.5, Total: 8, Favorite Moneyline: -190, Underdog Moneyline: +160)
• 5/16/2025: 5-1 SEA (Favorite: Padres, Spread: -1.5, Total: 8.5, Favorite Moneyline: -166, Underdog Moneyline: +140)
• 9/11/2024: 5-2 SEA (Favorite: Mariners, Spread: -1.5, Total: 6.5, Favorite Moneyline: -108, Underdog Moneyline: -108)
• 9/10/2024: 7-3 SD (Favorite: Mariners, Spread: -1.5, Total: 7, Favorite Moneyline: -126, Underdog Moneyline: +108)
• 7/10/2024: 2-0 SEA (Favorite: Padres, Spread: -1.5, Total: 7.5, Favorite Moneyline: -144, Underdog Moneyline: +122)
• 7/9/2024: 8-3 SEA (Favorite: Mariners, Spread: -1.5, Total: 7.5, Favorite Moneyline: -138, Underdog Moneyline: +118)
• 8/9/2023: 6-1 SEA (Favorite: Padres, Spread: -1.5, Total: 8.5, Favorite Moneyline: -154, Underdog Moneyline: +130)
• 8/8/2023: 2-0 SEA (Favorite: Mariners, Spread: -1.5, Total: 8.5, Favorite Moneyline: -120, Underdog Moneyline: +102)
• 6/7/2023: 10-3 SD (Favorite: Padres, Spread: -1.5, Total: 7.5, Favorite Moneyline: -116, Underdog Moneyline: -102)

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