Louisville vs Arkansas College Basketball Prediction, Odds, Picks, Best Bets for Dec. 3

The Louisville Cardinals (7-0) will try to continue a seven-game winning streak when they visit the Arkansas Razorbacks (5-2) on December 3, 2025 at Bud Walton Arena.

Before you place your bet on this game at FanDuel Sportsbook, here are the NCAA basketball odds and spreads you need to know.

Louisville vs. Arkansas Game Info and Odds

• Game day: Wednesday, December 3, 2025
• Game time: 7:15 p.m. ET
• TV channel: ESPN
• Location: Fayetteville, Arkansas
• Arena: Bud Walton Arena

Louisville is a 2.5-point favorite over Arkansas on Wednesday and the total has been set at 166.5 points. Keep reading for some betting insights and trends before you decide to wager on the matchup.

Sign up for FanDuel Sportsbook and FanDuel Daily Fantasy today!

Louisville vs. Arkansas: ATS Betting Stats and Trends

• Louisville has won five games against the spread this season, while failing to cover twice.
• Arkansas is 4-3-0 ATS this year.
• Louisville (5-2) covers a higher percentage of games when it is favored by 2.5 points or more this season (71.4%) than Arkansas (1-1) does as a 2.5+-point underdog (50%).
• Against the spread last season, the Cardinals fared worse when played at home, covering eight times in 17 home games, and nine times in 11 road games.
• The Razorbacks were better against the spread at home (9-8-0) than on the road (5-5-0) last season.

Louisville vs. Arkansas: Moneyline Betting Stats

• Louisville has won in each of the two contests it has played as moneyline favorites this season.
• The Cardinals have been listed as a favorite of -142 or more on two occasions this season and won both games.
• Arkansas has been the moneyline underdog just two other times so far this season, and it lost both games.
• The Razorbacks have played as a moneyline underdog of +116 or longer in just two games this season, which they lost both.
• Louisville has an implied victory probability of 58.7% according to the moneyline set for this matchup.

Louisville vs. Arkansas Head-to-Head Comparison

• Louisville's +236 scoring differential (outscoring opponents by 33.7 points per game) is a result of scoring 96.7 points per game (fourth in college basketball) while allowing 63.0 per outing (13th in college basketball).
• Louisville's leading scorer, Ryan Conwell, is 33rd in college basketball scoring 20.1 points per game.
• Arkansas' +116 scoring differential (outscoring opponents by 16.5 points per game) is a result of putting up 88.1 points per game (45th in college basketball) while allowing 71.6 per contest (146th in college basketball).
• Meleek Thomas' 17.6 points per game paces Arkansas and ranks 115th in the country.
• The Cardinals are third in college basketball at 43.6 rebounds per game. That's 12.9 more than the 30.7 their opponents average.
• Sananda Fru tops the Cardinals with 5.9 rebounds per game (349th in college basketball play).
• The Razorbacks win the rebound battle by 3.3 boards on average. They collect 34.9 rebounds per game, 125th in college basketball, while their opponents grab 31.6.
• Trevon Brazile averages 7.7 rebounds per game (108th in college basketball) to lead the Razorbacks.
• Louisville averages 114.6 points per 100 possessions on offense (eighth in college basketball), and allows 74.7 points per 100 possessions (third in college basketball).
• The Razorbacks' 106.9 points per 100 possessions on offense rank 46th in college basketball, and the 86.8 points they concede per 100 possessions rank 98th in college basketball.

Sign up for FanDuel Sportsbook and FanDuel Daily Fantasy today!