Kentucky vs Loyola (MD) College Basketball Prediction, Odds, Picks, Best Bets for Nov. 21

The Kentucky Wildcats (3-2) hit the court against the Loyola (MD) Greyhounds (2-4) on November 21, 2025.

Before you place your bet on this matchup at FanDuel Sportsbook, here are the NCAA basketball odds and spreads you need to know.

Kentucky vs. Loyola (MD) Game Info and Odds

• Game day: Friday, November 21, 2025
• Game time: 7 p.m. ET
• TV channel: SEC Network+
• Location: Lexington, Kentucky
• Arena: Rupp Arena

Here's a look at some betting trends and insights for Kentucky (-35.5) versus Loyola (MD) on Friday. The over/under has been set at 158.5 points for this game.

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Kentucky vs. Loyola (MD): ATS Betting Stats and Trends

• Kentucky has a record of 2-3-0 against the spread this season.
• Loyola (MD) is 3-2-0 ATS this season.
• The Wildcats sported a better record against the spread at home (10-8-0) than they did on the road (4-6-0) last season.
• The Greyhounds were better against the spread away (10-7-0) than at home (5-8-0) last year.

Kentucky vs. Loyola (MD) Head-to-Head Comparison

• Kentucky was the seventh-best team in college basketball in points scored (84.4 per game) and 315th in points conceded (77.2) last season.
• Kentucky was 63rd in the nation in rebounds per game (34.1) and 239th in rebounds allowed (32.1) last year.
• At 16.9 assists per game, Kentucky was 17th-best in the nation last season.
• In terms of turnovers, Kentucky was 108th in the nation in committing them (10.4 per game) last season. It was 312th in forcing them (9.9 per game).
• Loyola (MD) ranked 299th in college basketball last season with 69.2 points per game. At the other end of the court, it ranked 148th with 71.1 points allowed per game.
• Loyola (MD) grabbed 30.5 boards per game (271st-ranked in college basketball). It gave up 29.9 rebounds per contest (94th-ranked).
• Loyola (MD) delivered 13.7 dimes per game, which ranked them 165th in the nation.
• Loyola (MD) committed 11.3 turnovers per game (201st-ranked in college basketball). It forced 11.4 turnovers per contest (166th-ranked).

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