The James Madison Dukes will face the South Alabama Jaguars in college football action on Saturday.

Get the latest NCAA football odds ahead of this matchup on FanDuel Sportsbook.

James Madison vs South Alabama Odds & Spread

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• All college football odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: James Madison: (-140) | South Alabama: (+116)
• Spread: James Madison: -2.5 (-114) | South Alabama: +2.5 (-106)
• Total: 48.5 -- Over: (-110) | Under: (-110)

James Madison vs South Alabama Betting Trends

• James Madison has won twice against the spread this year.
• James Madison owns one win ATS (1-2) as a 2.5-point favorite or greater this year.
• Two of James Madison's four games have gone over the point total.
• South Alabama has one win against the spread this year.
• South Alabama has one win ATS (1-1) as a 2.5-point underdog or more this season.
• Two South Alabama games (of four) have gone over the point total this year.

James Madison vs South Alabama Prediction & Pick

All college football win probability predictions and picks are according to numberFire.
Prediction: Dukes win (70%)

James Madison vs South Alabama Point Spread

South Alabama is a 2.5-point underdog against James Madison. South Alabama is -106 to cover the spread, and James Madison is -114.

James Madison vs South Alabama Over/Under

A total of 48.5 points has been set for the James Madison-South Alabama game on September 30, with the over available at -110 and the under at -110.

James Madison vs South Alabama Moneyline

The James Madison vs South Alabama moneyline has James Madison as a -140 favorite, while South Alabama is a +116 underdog.

James Madison vs. South Alabama Points Insights

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Check out even more in-depth James Madison vs. South Alabama analysis on FanDuel Research.