Islanders vs Sharks NHL Prediction, Odds, Picks, Best Bets for Oct. 21

The NHL's Tuesday schedule includes the New York Islanders taking on the San Jose Sharks.

Before you make your wager on FanDuel Sportsbook, we've got you covered, in terms of the vital information regarding today's NHL betting odds.

Islanders vs Sharks Game Info

• New York Islanders (2-3) vs. San Jose Sharks (0-3-2)
• Date: Tuesday, October 21, 2025
• Time: 7 p.m. ET
• Venue: UBS Arena -- Elmont, New York
• Coverage: ESPN+

Islanders vs Sharks Odds

All NHL odds, betting lines and prop bets are available on FanDuel Sportsbook.

Islanders vs Sharks Prediction & Pick

All NHL win probability predictions and picks are according to numberFire.

• Prediction: Islanders win (58.8%)

Islanders vs Sharks Puck Line

• The Islanders are favored by 1.5 goals. The Islanders are +114 to cover the spread, with the Sharks being -140.

Islanders vs Sharks Over/Under

• Islanders versus Sharks, on Oct. 21, has an over/under of 6.5, with the over being -105 and the under -115.

Islanders vs Sharks Moneyline

• The Islanders vs Sharks moneyline has New York as a -215 favorite, while San Jose is a +176 underdog on the road.

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