Iowa vs Nebraska Prediction, Odds, Picks, Best Bets for Week 14 2025

The Iowa Hawkeyes will take on the Nebraska Cornhuskers in college football action on Friday.

We've got you covered, in terms of the vital information about NCAA football betting lines, before you make your wager on FanDuel Sportsbook.

Iowa vs Nebraska Odds & Spread

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• All college football odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: Iowa: (-230) | Nebraska: (+190)
• Spread: Iowa: -6.5 (-104) | Nebraska: +6.5 (-118)
• Total: 39.5 -- Over: (-110) | Under: (-110)

Iowa vs Nebraska Betting Trends

• Iowa has beaten the spread eight times in 11 games.
• As at least a 6.5-point favorite, Iowa has two wins ATS (2-2).
• This season, four of Iowa's 11 games have gone over the point total.
• Nebraska's record against the spread in 2025 is 4-7-0.
• Nebraska has no wins ATS (0-1) as a 6.5-point underdog or more this year.
• There have been eight Nebraska games (out of 11) that hit the over this year.

Iowa vs Nebraska Prediction & Pick

All college football win probability predictions and picks are according to numberFire.
Prediction: Hawkeyes win (57.3%)

Iowa vs Nebraska Point Spread

Nebraska is the underdog by 6.5 points against Iowa. Nebraska is -104 to cover the spread, and Iowa is -118.

Iowa vs Nebraska Over/Under

The over/under for the Iowa versus Nebraska matchup on Nov. 28 has been set at 39.5, with -110 odds on the over and -110 odds on the under.

Iowa vs Nebraska Moneyline

The moneyline numbers for Iowa vs. Nebraska reveal Iowa as the favorite (-230) and Nebraska as the underdog (+190).

Iowa vs. Nebraska Points Insights

Iowa vs. Nebraska Game Info

• Game day: Friday, November 28, 2025
• Game time: 12 p.m. ET
• TV channel: CBS
• Location: Lincoln, Nebraska
• Stadium: Memorial Stadium (Lincoln, NE)

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Check out even more in-depth Iowa vs. Nebraska analysis on FanDuel Research.