Illinois vs Southern College Basketball Prediction, Odds, Picks, Best Bets for Dec. 29

The Southern Jaguars (4-8) will try to stop a four-game losing streak when they visit the Illinois Fighting Illini (9-3) on December 29, 2025 at State Farm Center. The matchup airs on BTN.

Before you place your bet on this matchup at FanDuel Sportsbook, here are the NCAA basketball odds and spreads you need to know.

Illinois vs. Southern Game Info and Odds

• Game day: Monday, December 29, 2025
• Game time: 3 p.m. ET
• TV channel: Big Ten Network
• Location: Champaign, Illinois
• Arena: State Farm Center

Before making a wager on Monday's Illinois-Southern spread (Illinois -32.5) or total (163.5 points), take a look at the betting trends and insights below.

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Illinois vs. Southern: ATS Betting Stats and Trends

• Illinois has compiled a 7-5-0 record against the spread this season.
• Southern has compiled a 4-5-0 ATS record so far this year.
• The Fighting Illini owned a better record against the spread at home (10-7-0) than they did on the road (5-5-0) last season.
• Against the spread last season, the Jaguars had better results away (9-9-0) than at home (4-5-0).

Illinois vs. Southern Head-to-Head Comparison

• Illinois outscores opponents by 18.5 points per game (scoring 88.1 per game to rank 33rd in college basketball while allowing 69.6 per contest to rank 97th in college basketball) and has a +222 scoring differential overall.
• Keaton Wagler's team-leading 15.7 points per game ranks 225th in college basketball.
• Southern outscores opponents by 2.7 points per game (posting 85.3 points per game, 59th in college basketball, and allowing 82.6 per outing, 337th in college basketball) and has a +33 scoring differential.
• Michael Jacobs is ranked 20th in the country with a team-high 20.9 points per game.
• The Fighting Illini come out on top in the rebound battle by an average of 11.2 boards. They are grabbing 39 rebounds per game (16th in college basketball) compared to their opponents' 27.8 per contest.
• David Mirkovic's 8.5 rebounds per game lead the Fighting Illini and rank 55th in college basketball play.
• The Jaguars rank 165th in the nation at 33.7 rebounds per game. That's similar to the 34.3 their opponents average.
• Malek Abdelgowad is 117th in the country with 7.4 rebounds per game, leading the Jaguars.
• Illinois ranks 16th in college basketball with 110.9 points scored per 100 possessions, and 86th in college basketball defensively with 87.6 points conceded per 100 possessions.
• The Jaguars' 98.1 points per 100 possessions on offense rank 176th in college basketball, and the 94.9 points they concede per 100 possessions rank 242nd in college basketball.

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