Houston vs TCU College Basketball Prediction, Odds, Picks, Best Bets for Jan. 28

The No. 10 Houston Cougars (17-2, 5-1 Big 12) visit the TCU Horned Frogs (13-7, 3-4 Big 12) in Big 12 play at Ed and Rae Schollmaier Arena, beginning at 9 p.m. ET on Wednesday, January 28, 2026.

Before you place your bet on this game at FanDuel Sportsbook, here are the NCAA basketball odds and spreads you need to know.

Houston vs. TCU Game Info and Odds

• Game day: Wednesday, January 28, 2026
• Game time: 9 p.m. ET
• TV channel: ESPN2
• Location: Fort Worth, Texas
• Arena: Ed and Rae Schollmaier Arena

Houston vs. TCU Picks and Prediction

All college basketball win probability predictions and picks are according to numberFire.
Prediction: Houston win (66.3%)

Take a look at these betting insights and trends before you wager on Wednesday's Houston-TCU spread (Houston -7.5) or over/under (138.5 points).

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Houston vs. TCU: ATS Betting Stats and Trends

• Houston is 10-9-0 ATS this season.
• TCU has won 11 games against the spread this season, while failing to cover nine times.
• As a 7.5-point underdog or more in 2025-26, TCU is 4-0 against the spread compared to the 7-7 ATS record Houston racks up as a 7.5-point favorite.
• At home last season, the Cougars sported a worse record against the spread (10-7-0) compared to their ATS record in road games (7-3-0).
• In 2025-26 against the spread, the Horned Frogs have a lower winning percentage at home (.385, 5-8-0 record) than on the road (.750, 3-1-0).
• Houston has four wins against the spread in six conference games this year.
• Against the spread in Big 12 games, TCU is 4-3-0 this year.

Houston vs. TCU: Moneyline Betting Stats

• Houston has been victorious in 13, or 86.7%, of the 15 contests it has been chosen as moneyline favorites in this season.
• The Cougars have been a -420 moneyline favorite on eight occasions this season and won every game.
• TCU has won 42.9% of the games this season it was the underdog on the moneyline (3-4).
• The Horned Frogs have played as a moneyline underdog of +320 or longer in only two games this season, which they split 1-1.
• The moneyline set for this matchup implies Houston has a 80.8% chance of walking away with the win.

Houston vs. TCU Head-to-Head Comparison

• Houston's +331 scoring differential (outscoring opponents by 17.5 points per game) is a result of scoring 79.1 points per game (128th in college basketball) while giving up 61.6 per outing (third in college basketball).
• Kingston Flemings' team-leading 17 points per game ranks 140th in the nation.
• TCU's +193 scoring differential (outscoring opponents by 9.6 points per game) is a result of putting up 80 points per game (108th in college basketball) while giving up 70.4 per outing (98th in college basketball).
• David Punch leads TCU, recording 14.6 points per game (327th in college basketball).
• The Cougars prevail in the rebound battle by an average of 4.6 boards. They are collecting 33.3 rebounds per game (132nd in college basketball) compared to their opponents' 28.7 per outing.
• Chris Cenac Jr. averages 7.6 rebounds per game (ranking 104th in college basketball) to lead the Cougars.
• The Horned Frogs come out on top in the rebound battle by an average of two boards. They are grabbing 32 rebounds per game (213th in college basketball) compared to their opponents' 30.
• Punch tops the team with 7.8 rebounds per game (88th in college basketball).
• Houston scores 103.6 points per 100 possessions (62nd in college basketball), while allowing 80.7 points per 100 possessions (first in college basketball).
• The Horned Frogs rank 124th in college basketball with 100.2 points scored per 100 possessions, and 56th defensively with 88.1 points conceded per 100 possessions.

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