Gonzaga vs Pepperdine College Basketball Prediction, Odds, Picks, Best Bets for Jan. 21

The Gonzaga Bulldogs (19-1, 7-0 WCC) will host the Pepperdine Waves (6-14, 1-6 WCC) after winning 11 home games in a row.

Before you place your bet on this game at FanDuel Sportsbook, here are the NCAA basketball odds and spreads you need to know.

Gonzaga vs. Pepperdine Game Info and Odds

• Game day: Wednesday, January 21, 2026
• Game time: 9 p.m. ET
• TV channel: ESPN+
• Location: Spokane, Washington
• Arena: McCarthey Athletic Center

Gonzaga vs. Pepperdine Picks and Prediction

All college basketball win probability predictions and picks are according to numberFire.
Prediction: Gonzaga win (99.3%)

Gonzaga is a 28.5-point favorite against Pepperdine on Wednesday and the over/under has been set at 149.5 points. Keep reading for a few betting insights and trends to help you make an informed wager on the contest.

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Gonzaga vs. Pepperdine: ATS Betting Stats and Trends

• Gonzaga is 13-7-0 ATS this season.
• Pepperdine is 8-10-0 ATS this season.
• Gonzaga covers the spread when it is a 28.5-point favorite or more 66.7% of the time. That's more often than Pepperdine covers as an underdog of 28.5 or more (50%).
• The Bulldogs sport a better record against the spread in home games (5-3-0) than they do in away games (3-2-0).
• In 2025-26 against the spread, the Waves have a lower winning percentage at home (.300, 3-7-0 record) than away (.714, 5-2-0).
• Against the spread, in conference games, Gonzaga is 4-3-0 this season.
• Against the spread in WCC action, Pepperdine is 3-4-0 this season.

Gonzaga vs. Pepperdine: Moneyline Betting Stats

• Gonzaga has won in 14, or 93.3%, of the 15 contests it has been named as the moneyline favorite in this year.
• The Bulldogs have played as a favorite of -33333 or more just one time this year and came away with a win in that game.
• Pepperdine has gone 3-11 in games it was the underdog on the moneyline (winning 21.4% of those games).
• The Waves have yet to play as a moneyline underdog of +4000 or longer.
• The moneyline set for this matchup implies Gonzaga has a 99.7% chance of walking away with the win.

Gonzaga vs. Pepperdine Head-to-Head Comparison

• Offensively, Gonzaga was the second-best squad in the nation (86.4 points per game) last season. Defensively, it was 107th (69.9 points allowed per game).
• With 34.6 rebounds per game and 28.9 rebounds allowed, Gonzaga was 47th and 47th in the nation, respectively, last season.
• Gonzaga was best in the country in assists (19.7 per game) last season.
• In terms of turnovers, Gonzaga was 25th-best in college basketball in committing them (9.3 per game) last year. It was 140th in forcing them (11.7 per game).
• Pepperdine was 199th in the nation last season with 73.1 points per game. At the other end of the court, it ranked 306th with 76.6 points allowed per contest.
• Pepperdine grabbed 31.5 rebounds per game (200th-ranked in college basketball). It gave up 32.4 rebounds per contest (265th-ranked).
• Pepperdine ranked 46th in college basketball with 15.8 dimes per contest.
• With 10.3 turnovers per game, Pepperdine was 98th in the country. It forced 10.3 turnovers per contest, which ranked 274th in college basketball.

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