Giants vs Orioles Prediction, Odds, Moneyline, Spread & Over/Under for Aug. 29

Odds updated as of 10:14 p.m.

The Baltimore Orioles versus the San Francisco Giants is on the MLB schedule for Friday.

We've got you covered, in terms of the most important information regarding this matchup before you take a look at the MLB odds and spreads on FanDuel Sportsbook.

Orioles vs Giants Game Info

• Baltimore Orioles (60-74) vs. San Francisco Giants (66-68)
• Date: Friday, August 29, 2025
• Time: 10:15 p.m. ET
• Venue: Oracle Park -- San Francisco, California
• Coverage: Apple TV+

Orioles vs Giants Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: BAL: (-124) | SF: (+106)
• Spread: BAL: -1.5 (+126) | SF: +1.5 (-152)
• Total: 7.5 -- Over: (-122) | Under: (-100)

Orioles vs Giants Probable Starting Pitchers

Probable Pitchers: Dean Kremer (Orioles) - 9-9, 4.19 ERA vs Robbie Ray (Giants) - 10-6, 2.93 ERA

The Orioles will give the ball to Dean Kremer (9-9, 4.19 ERA), who is eyeing win No. 10 on the season, and the Giants will counter with Robbie Ray (10-6, 2.93 ERA). Kremer's team is 13-12-0 against the spread in his starts this season. When Kremer starts a game and his team is the favorite on the moneyline, they have a record of 5-7. The Giants have a 16-10-0 record against the spread in Ray's starts. The Giants have been the moneyline underdog in eight of Ray's starts this season, and they went 6-2 in those games.

Orioles vs Giants Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Giants win (56.2%)

Orioles vs Giants Moneyline

• Baltimore is a -124 favorite on the moneyline, while San Francisco is a +106 underdog at home.

Orioles vs Giants Spread

• The Orioles are at the Giants and are favored by 1.5 runs (+126 to cover) on the runline. San Francisco is -152 to cover.

Orioles vs Giants Over/Under

• The over/under for Orioles-Giants on Aug. 29 is 7.5. The over is -122, and the under is -100.

Bet on Baltimore Orioles vs. San Francisco Giants on FanDuel today!

Orioles vs Giants Betting Trends

• The Orioles have come away with 25 wins in the 56 contests they have been listed as the favorites in this season.
• This year Baltimore has won 19 of 38 games when listed as at least -124 on the moneyline.
• The Orioles' games have gone over the total in 56 of their 131 opportunities.
• The Orioles are 62-69-0 against the spread in their 131 games that had a posted line this season.
• The Giants are 25-28 in games they were the underdog on the moneyline (winning 47.2% of those games).
• When it has played as a moneyline underdog with odds of +106 or longer, San Francisco has gone 19-20 (48.7%).
• The Giants have played in 133 games with an over/under set, and have combined with opponents to go over the total 61 times (61-65-7).
• The Giants have gone 59-74-0 ATS this season.

Orioles Player Leaders

• Gunnar Henderson has 132 hits and an OBP of .348 to go with a slugging percentage of .461. All three of those stats lead Baltimore hitters this season. He has a .277 batting average, as well.
• He ranks 33rd in batting average, 43rd in on-base percentage, and 49th in slugging among all qualified hitters in MLB.
• Jackson Holliday is hitting .242 with 18 doubles, two triples, 15 home runs and 38 walks, while slugging .377 with an on-base percentage of .303.
• His batting average is 114th among qualified players, his on-base percentage 126th, and his slugging percentage 132nd.
• Colton Cowser has 53 hits this season and has a slash line of .219/.284/.413.
• Ryan Mountcastle has four home runs, 23 RBI and a batting average of .251 this season.

Giants Player Leaders

• Rafael Devers has accumulated a team-high OBP (.378), and paces the Giants in hits (129). He's batting .258 and slugging.
• Including all qualifying hitters, he is 78th in batting average, while his on-base percentage ranks ninth and he is 35th in slugging.
• Devers enters this game on a three-game hitting streak. In his last five games he is hitting .438 with a double, two home runs, three walks and six RBIs.
• Jung Hoo Lee is batting .261 with 30 doubles, 10 triples, seven home runs and 41 walks. He's slugging .409 with an on-base percentage of .323.
• He is currently 70th in batting average, 88th in on-base percentage and 97th in slugging percentage among all qualified hitters.
• Willy Adames is batting .224 with 18 doubles, two triples, 24 home runs and 64 walks.
• Heliot Ramos is slugging .408 to lead his team.

Sign up for FanDuel Sportsbook and FanDuel Daily Fantasy today!