Dodgers vs Orioles Prediction, Odds, Moneyline, Spread & Over/Under for Sept. 5

Odds updated as of 2:12 a.m.

Friday's slate in the MLB includes a matchup between the Los Angeles Dodgers and the Baltimore Orioles.

We've got you covered, in terms of the vital info regarding this game before you take a look at the MLB odds and spreads on FanDuel Sportsbook.

Dodgers vs Orioles Game Info

• Los Angeles Dodgers (78-62) vs. Baltimore Orioles (64-76)
• Date: Friday, September 5, 2025
• Time: 7:05 p.m. ET
• Venue: Oriole Park at Camden Yards -- Baltimore, Maryland
• Coverage: MASN and SportsNet LA

Dodgers vs Orioles Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: LAD: (-164) | BAL: (+138)
• Spread: LAD: -1.5 (-110) | BAL: +1.5 (-110)
• Total: 8.5 -- Over: (-115) | Under: (-105)

Dodgers vs Orioles Probable Starting Pitchers

Probable Pitchers: Tyler Glasnow (Dodgers) - 1-3, 3.41 ERA vs Dean Kremer (Orioles) - 9-10, 4.52 ERA

The probable pitchers are Tyler Glasnow (1-3) for the Dodgers and Dean Kremer (9-10) for the Orioles. Glasnow's team is 2-12-0 against the spread in his starts this season. Glasnow's team has won 42.9% of his starts when they are favored on the moneyline (6-8). The Orioles have a 13-13-0 ATS record in Kremer's 26 starts that had a set spread. The Orioles have a 5-9 record in Kremer's 14 starts this season when they were the underdog on the moneyline.

Dodgers vs Orioles Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Dodgers win (59.6%)

Dodgers vs Orioles Moneyline

• The moneyline numbers for Dodgers vs. Orioles reveal Los Angeles as the favorite (-164) and Baltimore as the underdog (+138) despite being the home team.

Dodgers vs Orioles Spread

• The Dodgers are favored by 1.5 runs on the road versus the Orioles. The Dodgers are -110 to cover the spread, while the Orioles are -110.

Dodgers vs Orioles Over/Under

• A combined run total of 8.5 has been set for Dodgers-Orioles on Sept. 5, with the over at -115 and the under at -105.

Bet on Los Angeles Dodgers vs. Baltimore Orioles on FanDuel today!

Dodgers vs Orioles Betting Trends

• The Dodgers have come away with 69 wins in the 122 contests they have been listed as the favorites in this season.
• Los Angeles has a record of 42-34 in contests when bookmakers favor them by -164 or more on the moneyline.
• Contests with the Dodgers have gone over the total set by bookmakers in 67 of 138 chances this season.
• The Dodgers are 56-82-0 against the spread in their 138 games with a line set by sportsbooks this season.
• The Orioles have won 45.5% of the games this season they were the underdog on the moneyline (35-42).
• When it has played as a moneyline underdog with odds of +138 or longer, Baltimore has an 8-10 record (winning 44.4% of its games).
• The Orioles have played in 137 games with an over/under set, and have combined with opponents to go over the total 60 times (60-73-4).
• The Orioles have covered 48.2% of their games this season, going 66-71-0 against the spread.

Dodgers Player Leaders

• Shohei Ohtani leads Los Angeles with 148 hits and a team-best slugging percentage of .606. He's batting .279 with an on-base percentage of .387.
• He is 27th in batting average, seventh in on-base percentage, and second in slugging among qualifying hitters in baseball.
• Mookie Betts has 18 doubles, a triple, 15 home runs and 54 walks. He's batting .250 and slugging .379 with an on-base percentage of .322.
• Among all qualifying hitters, he ranks 95th in batting average, 91st in on-base percentage and 129th in slugging percentage.
• Freddie Freeman has 139 hits this season and has a slash line of .294/.368/.489.
• Andy Pages has been key for Los Angeles with 138 hits, an OBP of .314 plus a slugging percentage of .462.

Orioles Player Leaders

• Gunnar Henderson has accumulated an on-base percentage of .349, a slugging percentage of .455, and has 138 hits, all club-highs for the Orioles (while batting .278).
• Including all the qualified hitters in the big leagues, his batting average ranks 31st, his on-base percentage is 44th, and he is 54th in slugging.
• Jackson Holliday is batting .249 with 20 doubles, three triples, 16 home runs and 45 walks. He's slugging .391 with an on-base percentage of .315.
• He is 97th in batting average, 107th in on-base percentage and 117th in slugging percentage in the big leagues.
• Ryan Mountcastle has 17 doubles, five home runs and 13 walks while hitting .266.
• Colton Cowser is batting .214 with 12 doubles, 13 home runs and 17 walks.

Sign up for FanDuel Sportsbook and FanDuel Daily Fantasy today!