Diamondbacks vs Pirates Prediction, Odds, Moneyline, Spread & Over/Under for July 25

Odds updated as of 6:13 p.m.

In MLB action on Friday, the Arizona Diamondbacks take on the Pittsburgh Pirates.

All the information you need to make smart wagers on this matchup at FanDuel Sportsbook can be found below. Check out all of the latest MLB betting lines here.

Diamondbacks vs Pirates Game Info

• Arizona Diamondbacks (50-53) vs. Pittsburgh Pirates (42-61)
• Date: Friday, July 25, 2025
• Time: 6:40 p.m. ET
• Venue: PNC Park -- Pittsburgh, Pennsylvania
• Coverage: SportsNet PT and ARID

Diamondbacks vs Pirates Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: ARI: (-116) | PIT: (-102)
• Spread: ARI: -1.5 (+140) | PIT: +1.5 (-170)
• Total: 9 -- Over: (-104) | Under: (-118)

Diamondbacks vs Pirates Probable Starting Pitchers

Probable Pitchers: Ryne Nelson (Diamondbacks) - 6-2, 3.52 ERA vs Mike Burrows (Pirates) - 1-3, 4.70 ERA

The Diamondbacks will give the nod to Ryne Nelson (6-2, 3.52 ERA), who is eyeing win No. 7 on the season, and the Pirates will turn to Mike Burrows (1-3, 4.70 ERA). Nelson and his team are 9-2-0 ATS this season when he starts. When Nelson starts a game and his team is the favorite on the moneyline, they have a record of 4-2. When Burrows starts, the Pirates are 5-4-0 against the spread. The Pirates have a 3-5 record in Burrows' eight starts this season when they were the underdog on the moneyline.

Diamondbacks vs Pirates Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Diamondbacks win (57%)

Diamondbacks vs Pirates Moneyline

• Arizona is the favorite, -116 on the moneyline, while Pittsburgh is a -102 underdog despite being at home.

Diamondbacks vs Pirates Spread

• The Pirates are hosting the Diamondbacks, and are +1.5 on the runline. The Pirates are +140 to cover the spread, and the Diamondbacks are -170.

Diamondbacks vs Pirates Over/Under

• The over/under for Diamondbacks-Pirates on July 25 is 9. The over is -104, and the under is -118.

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Diamondbacks vs Pirates Betting Trends

• The Diamondbacks have won in 32, or 49.2%, of the 65 contests they have been named as odds-on favorites in this year.
• This season Arizona has come away with a win 27 times in 55 chances when named as a favorite of at least -116 on the moneyline.
• The Diamondbacks and their opponents have gone over in 52 of their 100 games with a total set by sportsbooks this season.
• In 100 games with a line this season, the Diamondbacks have a mark of 47-53-0 against the spread.
• The Pirates have won 27 of the 67 games they were listed as the moneyline underdog this season (40.3%).
• Pittsburgh has gone 23-36 when it has played as a moneyline underdog with odds of -102 or longer (39%).
• The Pirates have had an over/under set by oddsmakers 96 times, and have combined with opponents to go over the total in 37 of those games (37-56-3).
• The Pirates have covered 51% of their games this season, going 49-47-0 ATS.

Diamondbacks Player Leaders

• Geraldo Perdomo leads Arizona OPS (.813) this season. He has a .283 batting average, an on-base percentage of .381, and a slugging percentage of .432.
• Among all qualifying hitters in MLB, he ranks 30th in batting average, ninth in on-base percentage, and 72nd in slugging.
• Perdomo will look for his third straight game with a hit in this contest. During his last five outings he is hitting .550 with two doubles, a walk and five RBIs.
• Eugenio Suarez leads Arizona in total hits (93) this season while batting .252 with 54 extra-base hits. He's slugging .593 with an on-base percentage of .325.
• Among all qualified, he ranks 99th in batting average, 83rd in on-base percentage and fourth in slugging percentage.
• Corbin Carroll has collected 87 base hits, an OBP of .325 and a slugging percentage of .557 this season.
• Carroll enters this matchup with five games in a row with at least one hit. In his last five games he is batting .364 with three doubles, three triples and three RBIs.
• Ketel Marte is batting .287 with a .389 OBP and 41 RBI for Arizona this season.

Pirates Player Leaders

• Oneil Cruz has racked up 72 hits, a team-high for the Pirates. He's batting .219 and slugging .419 with an on-base percentage of .319.
• Including all qualifying hitters, he is 149th in batting average, while his on-base percentage ranks 99th and he is 84th in slugging.
• Bryan Reynolds leads his team with a .382 slugging percentage. He has a batting average of .237 with an on-base percentage of .294.
• Including all qualifying players, he is 126th in batting average, 139th in on-base percentage and 125th in slugging percentage.
• Andrew McCutchen a has .335 on-base percentage to pace the Pirates.
• Isiah Kiner-Falefa has 12 doubles, two triples, a home run and 15 walks while hitting .271.

Diamondbacks vs Pirates Head to Head

• 5/28/2025: 10-1 PIT (Favorite: Diamondbacks, Spread: -1.5, Total: 7.5, Favorite Moneyline: -132, Underdog Moneyline: +112)
• 5/27/2025: 9-6 PIT (Favorite: Diamondbacks, Spread: -1.5, Total: 8.5, Favorite Moneyline: -260, Underdog Moneyline: +215)
• 5/26/2025: 5-0 ARI (Favorite: Diamondbacks, Spread: -1.5, Total: 9.5, Favorite Moneyline: -190, Underdog Moneyline: +160)
• 8/4/2024: 6-5 ARI (Favorite: Pirates, Spread: -1.5, Total: 7.5, Favorite Moneyline: -158, Underdog Moneyline: +134)
• 8/3/2024: 4-2 PIT (Favorite: Pirates, Spread: -1.5, Total: 8.5, Favorite Moneyline: -122, Underdog Moneyline: +104)
• 8/2/2024: 9-8 ARI (Favorite: Diamondbacks, Spread: -1.5, Total: 8.5, Favorite Moneyline: -134, Underdog Moneyline: +114)
• 7/28/2024: 6-5 PIT (Favorite: Diamondbacks, Spread: -1.5, Total: 8.5, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 7/27/2024: 9-5 ARI (Favorite: Diamondbacks, Spread: -1.5, Total: 8.5, Favorite Moneyline: -184, Underdog Moneyline: +154)
• 7/26/2024: 4-3 ARI (Favorite: Diamondbacks, Spread: -1.5, Total: 8.5, Favorite Moneyline: -166, Underdog Moneyline: +140)
• 7/9/2023: 4-2 PIT (Favorite: Diamondbacks, Spread: -1.5, Total: 9, Favorite Moneyline: -162, Underdog Moneyline: +136)

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