Cubs vs Padres Prediction, Odds, Moneyline, Spread & Over/Under for NL Wild Card Game 3 on Oct. 2

Odds updated as of 4:13 p.m.

The Chicago Cubs versus the San Diego Padres in Game 3 of the NL Wild Card Series is on the MLB schedule for Thursday.

All the information you need to make smart wagers on this matchup at FanDuel Sportsbook can be found below. Check out all of the latest MLB betting lines here.

Cubs vs Padres Game Info

• Chicago Cubs (92-70) vs. San Diego Padres (90-72)
• Date: Thursday, October 2, 2025
• Time: 5:08 p.m. ET
• Venue: Wrigley Field -- Chicago, Illinois
• Coverage: ESPN

Cubs vs Padres Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: CHC: (-116) | SD: (-102)
• Spread: CHC: +1.5 (-205) | SD: -1.5 (+168)
• Total: 7.5 -- Over: (-112) | Under: (-108)

Cubs vs Padres Probable Starting Pitchers

Probable Pitchers: Jameson Taillon (Cubs) - 11-7, 3.68 ERA vs Yu Darvish (Padres) - 5-5, 5.37 ERA

The probable pitchers are Jameson Taillon (11-7, 3.68 ERA) for the Cubs and Yu Darvish (5-5, 5.37 ERA) for the Padres. When Taillon starts, his team is 11-10-0 against the spread this season. When Taillon starts a game and his team is the favorite on the moneyline, they have a record of 10-4. When Darvish starts, the Padres have gone 10-4-0 against the spread. The Padres have been the moneyline underdog in six of Darvish's starts this season, and they went 3-3 in those games.

Cubs vs Padres Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Cubs win (58.5%)

Cubs vs Padres Moneyline

• San Diego is the underdog, -102 on the moneyline, while Chicago is a -116 favorite at home.

Cubs vs Padres Spread

• The Padres are 1.5-run favorites against the spread for this matchup with the Cubs. The Padres are +168 to cover, while the Cubs are -205 to cover as a 1.5-run underdog on the runline.

Cubs vs Padres Over/Under

• A combined run total of 7.5 has been set for Cubs-Padres on Oct. 2, with the over at -112 and the under at -108.

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Cubs vs Padres Betting Trends

• The Cubs have been favorites in 110 games this season and have come away with the win 71 times (64.5%) in those contests.
• Chicago has a record of 70-37 when favored by -116 or more this year.
• Contests with the Cubs have gone over the total set by bookmakers in 74 of 159 chances this season.
• The Cubs are 76-83-0 against the spread in their 159 games with a line set by sportsbooks this season.
• The Padres have a 34-35 record in games they were the underdog on the moneyline (winning 49.3% of those games).
• When it has played as a moneyline underdog with odds of -102 or longer, San Diego has a 30-34 record (winning 46.9% of its games).
• The Padres have combined with opponents to go over the total 70 times this season for a 70-89-3 record against the over/under.
• The Padres have collected an 88-74-0 record ATS this season.

Cubs Player Leaders

• Kyle Tucker leads Chicago in OBP (.377) this season, fueled by 133 hits. He has a .266 batting average and a slugging percentage of .464.
• Among all qualifying batters in MLB, he is 46th in batting average, seventh in on-base percentage, and 44th in slugging.
• Nico Hoerner has hit seven homers this season while driving in 61 runs. He's batting .297 this season and slugging .394 with an on-base percentage of .345.
• He is eighth in batting average, 46th in on-base percentage and 110th in slugging in the majors.
• Hoerner has picked up a hit in three straight games. In his last five games he is hitting .286 with a home run and two RBIs.
• Pete Crow-Armstrong has collected 146 base hits, an OBP of .287 and a slugging percentage of .481 this season.
• Seiya Suzuki has been key for Chicago with 140 hits, an OBP of .326 plus a slugging percentage of .478.
• Suzuki brings a nine-game hitting streak into this game. In his last 10 outings he is hitting .294 with two doubles, six home runs, two walks and 13 RBIs.

Padres Player Leaders

• Fernando Tatis Jr. has racked up an on-base percentage of .368, a team-high for the Padres. He's batting .268 and slugging .446.
• Including all qualifying hitters in the majors, he is 43rd in batting average, 10th in on-base percentage and 60th in slugging percentage.
• Manny Machado's 169 hits pace his team. He has a batting average of .275 while slugging .460 with an on-base percentage of .335.
• Including all qualified hitters, his batting average places him 33rd, his on-base percentage ranks 58th, and he is 49th in slugging.
• Luis Arraez has put up a team-high .392 slugging percentage.
• Ryan O'Hearn has 21 doubles, a triple, 17 home runs and 58 walks while hitting .281.

Cubs vs Padres Head to Head

• 10/1/2025: 3-0 SD (Favorite: Cubs, Spread: -1.5, Total: 6.5, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 9/30/2025: 3-1 CHC (Favorite: Cubs, Spread: -1.5, Total: 6.5, Favorite Moneyline: -126, Underdog Moneyline: +108)
• 4/16/2025: 4-2 SD (Favorite: Padres, Spread: -1.5, Total: 7.5, Favorite Moneyline: -108, Underdog Moneyline: -108)
• 4/15/2025: 2-1 CHC (Favorite: Cubs, Spread: -1.5, Total: 8, Favorite Moneyline: -156, Underdog Moneyline: +132)
• 4/14/2025: 10-4 SD (Favorite: Padres, Spread: -1.5, Total: 7.5, Favorite Moneyline: -148, Underdog Moneyline: +126)
• 4/6/2025: 8-7 SD (Favorite: Cubs, Spread: -1.5, Total: 7.5, Favorite Moneyline: -142, Underdog Moneyline: +120)
• 4/5/2025: 7-1 CHC (Favorite: Cubs, Spread: -1.5, Total: 6.5, Favorite Moneyline: -118, Underdog Moneyline: -100)
• 4/4/2025: 3-1 CHC (Favorite: Cubs, Spread: -1.5, Total: 7, Favorite Moneyline: -168, Underdog Moneyline: +142)
• 5/8/2024: 3-0 SD (Favorite: Padres, Spread: -1.5, Total: 7.5, Favorite Moneyline: -134, Underdog Moneyline: +114)
• 5/7/2024: 3-2 CHC (Favorite: Cubs, Spread: -1.5, Total: 9, Favorite Moneyline: -166, Underdog Moneyline: +140)

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