Colts vs Cardinals Prediction, Odds, Picks, Best Bets for NFL Week 6

Sunday's slate in the NFL includes a matchup between the Indianapolis Colts and the Arizona Cardinals.

Before you place your bet on this game at FanDuel Sportsbook, here are the NFL moneyline insights you need to know.

Colts vs Cardinals Prediction & Pick

All NFL win probability predictions and picks are according to numberFire.
Prediction: Colts win (82.4%)

Colts vs Cardinals Point Spread

The Colts are 6.5-point favorites against the Cardinals. The Colts are -110 to cover the spread, while the Cardinals are -110 to cover as a 6.5-point underdog.

Colts vs Cardinals Over/Under

Colts versus Cardinals, on Oct. 12, has an over/under of 47.5, with the over being -105 and the under -115.

Colts vs Cardinals Moneyline

Looking at the moneyline for Colts-Cardinals, Indianapolis is the favorite at -300, and Arizona is +245 playing on the road.

Colts vs Cardinals Betting Trends

• Indianapolis' record against the spread is 4-1-0.
• The Colts are unbeaten ATS (1-0) as a 6.5-point favorite or greater this year.
• Indianapolis has had two games (out of five) hit the over this year.
• The Cardinals have posted two wins against the spread this year.
• Two Cardinals games (out of five) have hit the over this year.

Check out even more in-depth Colts vs. Cardinals analysis on FanDuel Research.

Colts vs Cardinals Odds & Spread

• All NFL odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: IND: (-300) | ARI: (+245)
• Spread: IND: -6.5 (-110) | ARI: +6.5 (-110)
• Total: 47.5 -- Over: (-105) | Under: (-115)

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