Top 25 College Basketball Picks & Predictions Today - November 5

There is one game on Wednesday's schedule that involves a team ranked in the Top 25 in the AP Poll, as No. 23 Creighton is squaring off against South Dakota, with the opening tip at 8 p.m. ET. Below, we offer our pick and prediction for this matchup.

For analysis of all the important games in college basketball today, read our betting odds preview below.

Creighton vs. South Dakota

• Matchup: South Dakota Coyotes at No. 23 Creighton Bluejays
• Projected Winner: Creighton (95.53% win probability)
• Spread: Creighton (-29.5)
• Time: 8 p.m. ET
• Date: November 6
• TV Channel: Peacock

Bet on Creighton vs. South Dakota with FanDuel Sportsbook.

Matchup favorites and win projections are provided by numberFire.

For more college basketball betting insights, check out FanDuel Research's college basketball home page.

Sign up for FanDuel Sportsbook and FanDuel Daily Fantasy today!