Clippers vs. Lakers Prediction, Odds, Picks, Best Bets for Jan. 22

Clippers vs. Lakers Game Info

• Date: Thursday, January 22, 2026
• Time: 10 p.m. ET
• Venue: Intuit Dome -- Inglewood, California
• Coverage: Amazon Prime Video

The Los Angeles Clippers (19-24) are just 2.5-point favorites as they attempt to extend a three-game home winning streak when they take on the Los Angeles Lakers (26-16) on Thursday, January 22, 2026 at Intuit Dome. The matchup airs at 10 p.m. ET on Amazon Prime Video. The over/under for the matchup is set at 224.5.

Clippers vs. Lakers Odds & Spread

All NBA betting lines, odds and prop bets are from FanDuel Sportsbook.

Clippers vs. Lakers Prediction & Pick

All NBA win probability predictions and picks are according to numberFire.
Prediction:

Clippers vs. Lakers Betting Trends

• The Clippers have covered the spread 20 times this season (20-23-0).
• The Lakers have played 42 games, with 22 wins against the spread.
• Clippers games have gone over the total 23 times out of 42 chances this season.
• Lakers games this year have gone over the point total 59.5% of the time (25 out of 42 games with a set point total).
• The Clippers have covered the spread in a lower percentage of their home games than away games. They have covered nine times in 20 games when playing at home, and they've covered 11 times in 23 games on the road.
• At home, the Clippers eclipse the total 50% of the time (10 of 20 games). They hit the over more often in road games, exceeding the total in 56.5% of games (13 of 23).
• Against the spread, the Lakers have had better results on the road (12-10-0) than at home (10-9-1) .
• In 2025-26, a higher percentage of the Lakers' games have finished above the over/under at home (75%, 15 of 20) than on the road (45.5%, 10 of 22).

Clippers Leaders

• James Harden is averaging 26 points, 4.8 boards and 8 assists. Defensively, he averages 1.3 steals and 0.4 blocked shots.
• Kawhi Leonard is averaging 28.2 points, 3.5 assists and 6.3 boards.
• Ivica Zubac is averaging 14.8 points, 2.4 assists and 10.8 rebounds.
• John Collins is averaging 13.3 points, 4.9 rebounds and 0.8 assists.
• Kris Dunn's numbers on the season are 8 points, 3 rebounds and 3.2 assists per contest, shooting 48.7% from the floor and 37.8% from beyond the arc, with an average of 1.1 made treys.

Lakers Leaders

• Luka Doncic averages 33.5 points, 7.7 boards and 8.7 assists. He is also sinking 46.7% of his shots from the field and 33.7% from 3-point range, with 3.4 triples per game (sixth in league).
• The Lakers get 13.9 points per game from Deandre Ayton, plus 8.8 rebounds and 0.9 assists.
• The Lakers receive 22.5 points per game from LeBron James, plus 6 rebounds and 7 assists.
• Jake Laravia averages 9.5 points, 4.2 rebounds and 2 assists. He is draining 46.3% of his shots from the floor and 33.6% from 3-point range, with 1.2 treys per game.
• Marcus Smart's numbers on the season are 10 points, 3.1 boards and 2.8 assists per contest. He is making 40.7% of his shots from the field and 32.7% from beyond the arc, with an average of 1.7 treys.

For more NBA betting insights, check out FanDuel Research's NBA home page.

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