Clippers vs. Grizzlies Prediction, Odds, Picks, Best Bets for Nov. 28

Clippers vs. Grizzlies Game Info

• Date: Friday, November 28, 2025
• Time: 10 p.m. ET
• Venue: Intuit Dome -- Inglewood, California
• Coverage: FDSSE and FDSSC

The Los Angeles Clippers (5-13) host the Memphis Grizzlies (7-12) after losing five home games in a row. The Clippers are favored by 6.5 points in the contest, which tips at 10 p.m. ET on Friday, November 28, 2025. The matchup has an over/under of 227.5.

Clippers vs. Grizzlies Odds & Spread

All NBA betting lines, odds and prop bets are from FanDuel Sportsbook.

Clippers vs. Grizzlies Prediction & Pick

All NBA win probability predictions and picks are according to numberFire.
Prediction: Clippers win (64.2%)

Clippers vs. Grizzlies Betting Trends

• The Clippers have covered the spread five times this season (5-13-0).
• The Grizzlies have seven wins against the spread in 19 games this season.
• This season, Clippers games have hit the over 11 times out of 19 chances.
• Grizzlies games this year have hit the over on seven of 19 set point totals (36.8%).
• Los Angeles owns a worse record against the spread at home (1-7-0) than it does in away games (4-6-0).
• The Clippers have hit the over on the total in five of eight home games (62.5%), compared to six of 10 road games (60%).
• In 2025-26 against the spread, Memphis has a better winning percentage at home (.400, 4-6-0 record) than on the road (.333, 3-6-0).
• Grizzlies games have finished above the over/under more often at home (four times out of 10) than away (three of nine) this year.

Clippers Leaders

• James Harden is averaging 27.9 points, 8.4 assists and 5.7 boards.
• Ivica Zubac's numbers on the season are 16.6 points, 11.5 rebounds and 2.4 assists per game, shooting 61% from the field (ninth in league).
• John Collins is averaging 11.6 points, 4.8 boards and 0.6 assists. Defensively, he averages 0.8 steals and 0.6 blocked shots.
• Kawhi Leonard is averaging 23.1 points, 5.3 boards and 3.3 assists. Defensively, he averages 2.4 steals and 0.5 blocked shots.
• Kris Dunn averages 7.7 points, 2.4 rebounds and 2.7 assists, shooting 50% from the field.

Grizzlies Leaders

• Per game, Santi Aldama gives the Grizzlies 13.8 points, 6.6 boards and 2.8 assists. He also averages 1 steal and 0.8 blocks.
• Cedric Coward averages 13.7 points, 6 rebounds and 2.8 assists. He is also making 46.6% of his shots from the field and 37.5% from 3-point range, with 1.7 triples per game.
• Jaren Jackson Jr. averages 18.3 points, 5.3 rebounds and 1.6 assists. He is sinking 46.1% of his shots from the field and 35.6% from 3-point range, with 1.8 treys per game.
• Per game, Jock Landale provides the Grizzlies 11.2 points, 5.4 boards and 1.6 assists, plus 0.5 steals and 0.4 blocks.
• Per game, Jaylen Wells provides the Grizzlies 11.1 points, 3.4 rebounds and 1.7 assists, plus 0.7 steals and 0.1 blocks.

For more NBA betting insights, check out FanDuel Research's NBA home page.

Sign up for FanDuel Sportsbook and FanDuel Daily Fantasy today!

Watch FanDuel TV's NBA show "Run It Back" with Lou Williams, Michelle Beadle, DeMarcus "Boogie" Cousins and Chandler Parsons weekdays at 10am ET on FanDuel TV, the Run It Back YouTube page, or download the podcast here: fanduel.com/research/tv-and-podcast.