Clippers vs. Grizzlies Prediction, Odds, Picks, Best Bets for Nov. 28

Clippers vs. Grizzlies Game Info

• Date: Friday, November 28, 2025
• Time: 10 p.m. ET
• Venue: Intuit Dome -- Inglewood, California
• Coverage: FDSSE and FDSSC

The Los Angeles Clippers (5-13) are favored (by 6.5 points) to end a five-game home losing streak when they host the Memphis Grizzlies (7-12) on Friday, November 28, 2025 at 10 p.m. ET. The matchup's over/under is 224.5.

Clippers vs. Grizzlies Odds & Spread

All NBA betting lines, odds and prop bets are from FanDuel Sportsbook.

Clippers vs. Grizzlies Prediction & Pick

All NBA win probability predictions and picks are according to numberFire.
Prediction:

Clippers vs. Grizzlies Betting Trends

• The Clippers have covered the spread five times this season (5-13-0).
• The Grizzlies have played 19 games, with seven wins against the spread.
• Clippers games have gone over the total 11 times out of 19 chances this season.
• The Grizzlies have eclipsed the over/under 36.8% of the time this year (seven of 19 games with a set point total).
• Against the spread, Los Angeles has played worse when playing at home, covering one time in eight home games, and four times in 10 road games.
• The Clippers have gone over the over/under in a higher percentage of home games (62.5%) than away games (60%).
• Memphis' winning percentage against the spread at home is .400 (4-6-0). Away, it is .333 (3-6-0).
• In 2025-26, a higher percentage of the Grizzlies' games have finished above the over/under at home (40%, four of 10) than away (33.3%, three of nine).

Clippers Leaders

• James Harden is averaging 27.9 points, 8.4 assists and 5.7 boards.
• Ivica Zubac averages 16.6 points, 11.5 rebounds and 2.4 assists.
• John Collins averages 11.6 points, 4.8 boards and 0.6 assists, shooting 49.7% from the floor.
• Kawhi Leonard is averaging 23.1 points, 5.3 boards and 3.3 assists. At the other end, he averages 2.4 steals and 0.5 blocked shots.
• Kris Dunn averages 7.7 points, 2.4 boards and 2.7 assists, shooting 50% from the floor.

Grizzlies Leaders

• Santi Aldama is averaging 13.8 points, 6.6 rebounds and 2.8 assists for the Grizzlies.
• Cedric Coward averages 13.7 points, 6 rebounds and 2.8 assists. He is also draining 46.6% of his shots from the floor and 37.5% from 3-point range, with 1.7 triples per game.
• Per game, Jaren Jackson Jr. provides the Grizzlies 18.3 points, 5.3 rebounds and 1.6 assists, plus 0.6 steals and 1.2 blocks.
• The Grizzlies are receiving 11.2 points, 5.4 rebounds and 1.6 assists per game from Jock Landale.
• Jaylen Wells' numbers on the season are 11.1 points, 3.4 boards and 1.7 assists per game. He is draining 41.4% of his shots from the field and 33.3% from 3-point range, with an average of 1.7 treys.

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