Celtics vs. Pacers Prediction, Odds, Picks, Best Bets for Jan. 21

Celtics vs. Pacers Game Info

• Date: Wednesday, January 21, 2026
• Time: 7:30 p.m. ET
• Venue: TD Garden -- Boston, Massachusetts
• Coverage: FDSIN, NBCS-BOS, and WTHR-13

The Boston Celtics (26-16) are heavy, 11-point favorites against the Indiana Pacers (10-34) on Wednesday, January 21, 2026 at 7:30 p.m. ET. The matchup airs on FDSIN, NBCS-BOS, and WTHR-13. The matchup has a point total of 226.5.

Celtics vs. Pacers Odds & Spread

All NBA betting lines, odds and prop bets are from FanDuel Sportsbook.

Celtics vs. Pacers Prediction & Pick

All NBA win probability predictions and picks are according to numberFire.
Prediction: Celtics win (84%)

Celtics vs. Pacers Betting Trends

• The Celtics have covered the spread 24 times in 42 games with a set spread.
• The Pacers have 22 wins against the spread in 44 games this year.
• Celtics games have gone over the total 18 times out of 44 chances this season.
• Pacers games this year have hit the over 16 times in 44 opportunities (36.4%).
• Boston has a worse record against the spread when playing at home (9-10-0) than it does on the road (15-7-1).
• The Celtics have gone over the over/under in a higher percentage of games at home (47.4%) than away games (39.1%).
• In 2025-26 against the spread, Indiana has a better winning percentage at home (.583, 14-10-0 record) than away (.400, 8-12-0).
• Pacers games have finished above the over/under 41.7% of the time at home (10 of 24), and 30% of the time away (six of 20).

Celtics Leaders

• Jaylen Brown is averaging 29.8 points, 6.6 boards and 4.7 assists. Defensively, he averages 0.9 steals and 0.4 blocked shots.
• Derrick White's numbers on the season are 17.7 points, 4.6 rebounds and 5.4 assists per contest, shooting 39.1% from the floor and 32.4% from downtown, with an average of 3 made 3-pointers.
• Payton Pritchard's numbers on the season are 16.6 points, 4.4 boards and 5.3 assists per contest, shooting 45% from the field and 33.9% from downtown, with an average of 2.5 made treys.
• Neemias Queta is averaging 10.2 points, 8.2 rebounds and 1.4 assists.
• Anfernee Simons is averaging 14 points, 2.4 boards and 2.5 assists.

Pacers Leaders

• Pascal Siakam averages 23.6 points, 6.9 boards and 4 assists. He is also draining 48.1% of his shots from the field and 38% from beyond the arc, with 1.8 triples per game.
• The Pacers are getting 17.6 points, 2.6 rebounds and 7.1 assists per game from Andrew Nembhard.
• The Pacers get 8.8 points per game from Jay Huff, plus 3.8 boards and 1.3 assists.
• The Pacers receive 9 points per game from Jarace Walker, plus 4.3 boards and 1.9 assists.
• T.J. McConnell averages 9.9 points, 2.2 boards and 5 assists. He is making 54% of his shots from the field.

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