Cavaliers vs. Spurs Prediction, Odds, Picks, Best Bets for Dec. 5

Cavaliers vs. Spurs Game Info

• Date: Friday, December 5, 2025
• Time: 7:30 p.m. ET
• Venue: Rocket Arena -- Cleveland, Ohio
• Coverage: FDSOH and FDSSW

The Cleveland Cavaliers (13-10) are favored by 3.5 points against the San Antonio Spurs (15-6) on Friday, December 5, 2025 at 7:30 p.m. ET. The matchup airs on FDSOH and FDSSW. The over/under for the matchup is 238.5.

Cavaliers vs. Spurs Odds & Spread

All NBA betting lines, odds and prop bets are from FanDuel Sportsbook.

Cavaliers vs. Spurs Prediction & Pick

All NBA win probability predictions and picks are according to numberFire.
Prediction: Cavaliers win (78.7%)

Cavaliers vs. Spurs Betting Trends

• The Cavaliers have covered the spread eight times this season (8-15-0).
• The Spurs have played 21 games, with 10 wins against the spread.
• This season, Cavaliers games have hit the over 10 times out of 21 chances.
• The Spurs have hit the over 52.4% of the time this year (11 of 21 games with a set point total).
• Cleveland has covered the spread in a lower percentage of its home games than away games. It has covered four times in 13 games at home, and it has covered four times in 10 games on the road.
• In terms of point totals, the Cavaliers hit the over less consistently at home, as they've eclipsed the total three times in 13 opportunities this season (23.1%). On the road, they have hit the over seven times in 10 opportunities (70%).
• In 2025-26 against the spread, San Antonio has a better winning percentage at home (.545, 6-3-2 record) than away (.400, 4-5-1).
• Spurs games have gone above the over/under less frequently at home (five times out of 11) than away (six of 10) this season.

Cavaliers Leaders

• Donovan Mitchell is averaging 30.7 points, 5 boards and 5.5 assists. At the other end, he averages 1.4 steals and 0.3 blocked shots.
• Evan Mobley averages 19 points, 9 boards and 4.1 assists.
• De'Andre Hunter is averaging 16.7 points, 4.5 rebounds and 2.6 assists. Defensively, he averages 0.7 steals and 0.2 blocked shots.
• Jaylon Tyson is averaging 12.5 points, 5 rebounds and 1.8 assists. Defensively, he averages 1.2 steals and 0.7 blocked shots.
• Lonzo Ball is averaging 5.7 points, 4.5 rebounds and 4.9 assists.

Spurs Leaders

• Devin Vassell is averaging 15.7 points, 3.8 rebounds and 2.3 assists for the Spurs.
• Keldon Johnson's numbers on the season are 13 points, 6.5 rebounds and 1.9 assists per game. He is sinking 57.7% of his shots from the field (10th in NBA).
• The Spurs are receiving 25 points, 3.6 boards and 6.3 assists per game from De'Aaron Fox.
• Harrison Barnes' numbers on the season are 13.2 points, 3.4 boards and 2.2 assists per game. He is sinking 48.7% of his shots from the floor and 42.7% from beyond the arc, with an average of 2.4 treys.
• The Spurs get 10.9 points per game from Julian Champagnie, plus 5.4 rebounds and 1.4 assists.

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