Cavaliers vs. Grizzlies Prediction, Odds, Picks, Best Bets for Nov. 15

Cavaliers vs. Grizzlies Game Info

• Date: Saturday, November 15, 2025
• Time: 5 p.m. ET
• Venue: Rocket Arena -- Cleveland, Ohio
• Coverage: FDSOH, FDSSE, and NBA TV

The Memphis Grizzlies (4-9) are heavy underdogs (-11.5) as they try to stop a three-game road losing streak when they visit the Cleveland Cavaliers (8-5) on Saturday, November 15, 2025 at Rocket Arena. The matchup airs at 5 p.m. ET on FDSOH, FDSSE, and NBA TV. The matchup's point total is set at 240.5.

Cavaliers vs. Grizzlies Odds & Spread

All NBA betting lines, odds and prop bets are from FanDuel Sportsbook.

Cavaliers vs. Grizzlies Prediction & Pick

All NBA win probability predictions and picks are according to numberFire.
Prediction: Cavaliers win (74.6%)

Cavaliers vs. Grizzlies Betting Trends

• The Cavaliers have put together a record of 5-8-0 against the spread this season.
• The Grizzlies have played 13 games, with three wins against the spread.
• Cavaliers games have finished with a final combined score above the over/under eight times this season.
• Grizzlies games this season have hit the over five times in 13 opportunities (38.5%).
• Cleveland owns a worse record against the spread in home games (2-4-0) than it does in away games (3-4-0).
• When it comes to point totals, the Cavaliers hit the over less often in home games, as they've gone over the total three times in six opportunities this season (50%). In away games, they have hit the over five times in seven opportunities (71.4%).
• In 2025-26 against the spread, Memphis has a better winning percentage at home (.375, 3-5-0 record) than away (.000, 0-5-0).
• Grizzlies games have gone above the over/under less often at home (three times out of eight) than on the road (two of five) this year.

Cavaliers Leaders

• Donovan Mitchell is averaging 30.5 points, 4.5 boards and 5.5 assists. At the other end, he averages 1.5 steals and 0.5 blocked shots.
• Evan Mobley is averaging 19.0 points, 4.2 assists and 8.7 boards.
• Jarrett Allen's numbers on the season are 15.5 points, 7.9 boards and 1.7 assists per game, shooting 58.4% from the floor.
• De'Andre Hunter averages 18.9 points, 4.9 rebounds and 3.1 assists, shooting 43.8% from the floor and 27.8% from downtown, with 2.0 made treys per game.
• Craig Porter Jr. is averaging 5.7 points, 2.8 assists and 2.9 rebounds.

Grizzlies Leaders

• Ja Morant is averaging 18.9 points, 3.7 boards and 8.1 assists for the Grizzlies.
• Cedric Coward averages 14.3 points, 5.9 rebounds and 3.1 assists. He is also draining 48.4% of his shots from the floor and 37.5% from beyond the arc, with 1.6 treys per game.
• Jaren Jackson Jr.'s numbers on the season are 17.2 points, 5.2 rebounds and 1.3 assists per contest. He is making 50.9% of his shots from the floor and 39.6% from beyond the arc, with an average of 1.6 triples.
• Per game, Santi Aldama gets the Grizzlies 12.7 points, 6.5 boards and 2.5 assists, plus 1.1 steals and 0.6 blocks.
• The Grizzlies are receiving 10.7 points, 5.5 rebounds and 1.8 assists per game from Jock Landale.

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