Cardinals vs Rockies Prediction, Odds, Moneyline, Spread & Over/Under for July 21

Odds updated as of 12:11 p.m.

The MLB schedule on Monday includes the St. Louis Cardinals facing the Colorado Rockies.

Here's everything you need to know before checking out today's MLB odds and spreads on FanDuel Sportsbook.

Cardinals vs Rockies Game Info

• St. Louis Cardinals (51-49) vs. Colorado Rockies (24-75)
• Date: Monday, July 21, 2025
• Time: 8:40 p.m. ET
• Venue: Coors Field -- Denver, Colorado
• Coverage: COLR and FDSMW

Cardinals vs Rockies Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: STL: (-154) | COL: (+130)
• Spread: STL: -1.5 (-106) | COL: +1.5 (-113)
• Total: 11.5 -- Over: (-110) | Under: (-110)

Cardinals vs Rockies Probable Starting Pitchers

Probable Pitchers: Michael McGreevy (Cardinals) - 0-0, 0.00 ERA vs Austin Gomber (Rockies) - 0-3, 5.65 ERA

The Cardinals will give the nod to Michael McGreevy and the Rockies will counter with Austin Gomber (0-3, 5.65 ERA). McGreevy did not pitch as the moneyline favorite last season. The Rockies have a 1-5-0 ATS record in Gomber's six starts with a set spread. The Rockies are 1-5 in Gomber's six starts this season that they were the underdog on the moneyline.

Cardinals vs Rockies Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Cardinals win (62.8%)

Cardinals vs Rockies Moneyline

• The Cardinals vs Rockies moneyline has St. Louis as a -154 favorite, while Colorado is a +130 underdog at home.

Cardinals vs Rockies Spread

• The Cardinals are favored by 1.5 runs on the road against the Rockies. The Cardinals are -106 to cover the spread, while the Rockies are -113.

Cardinals vs Rockies Over/Under

• The over/under for the Cardinals versus Rockies game on July 21 has been set at 11.5, with -110 odds on the over and -110 odds on the under.

Bet on St. Louis Cardinals vs. Colorado Rockies on FanDuel today!

Cardinals vs Rockies Betting Trends

• The Cardinals have been victorious in 23, or 53.5%, of the 43 contests they have been chosen as favorites in this season.
• St. Louis has a record of 5-2 in contests when sportsbooks favor them by -154 or more on the moneyline.
• Contests with the Cardinals have gone over the total set by bookmakers in 52 of 97 chances this season.
• The Cardinals have an against the spread record of 52-45-0 in 97 games with a line this season.
• The Rockies have been the moneyline underdog 93 total times this season. They've finished 22-71 in those games.
• In games it has played as a moneyline underdog with odds of +130 or longer, Colorado has an 18-65 record (winning just 21.7% of its games).
• The Rockies have played in 97 games with an over/under set, and have combined with their opponents to go over the total 39 times (39-55-3).
• The Rockies have a 39-58-0 record against the spread this season.

Cardinals Player Leaders

• Brendan Donovan leads St. Louis with an OBP of .363, plus a team-best slugging percentage of .421. He's batting .291 on the season.
• Among qualifying batters, he ranks 16th in batting average, his on-base percentage ranks 31st, and he is 83rd in slugging.
• Alec Burleson leads St. Louis in total hits (88) this season while batting .293 with 29 extra-base hits. He's slugging .470 with an on-base percentage of .340.
• Among all qualifying players, he ranks 13th in batting average, 60th in on-base percentage and 42nd in slugging percentage.
• Burleson has picked up a hit in four games in a row. During his last five outings he is batting .313 with a home run, three walks and an RBI.
• Nolan Arenado has collected 79 base hits, an OBP of .299 and a slugging percentage of .381 this season.
• Masyn Winn has been key for St. Louis with 89 hits, an OBP of .322 plus a slugging percentage of .383.
• Winn enters this game on a four-game hitting streak. During his last five outings he is batting .350 with a walk.

Rockies Player Leaders

• Hunter Goodman has put up a team-high slugging percentage (.521) while leading the Rockies in hits (92). He's batting .279 and with an on-base percentage of .325.
• Including all qualifying players in the big leagues, his batting average places him 39th, his on-base percentage ranks 84th, and he is 14th in slugging.
• Jordan Beck's .328 on-base percentage leads his team. He has a batting average of .275 while slugging .463.
• His batting average ranks 47th among all qualified players, his on-base percentage is 77th, and he is 49th in slugging.
• Mickey Moniak is hitting .267 with 11 doubles, six triples, 14 home runs and 16 walks.
• Ryan McMahon is hitting .217 with 15 doubles, a triple, 15 home runs and 46 walks.

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