Canadiens vs Sabres NHL Prediction, Odds, Picks, Best Bets for Jan. 22

The Thursday schedule in the NHL includes a matchup between the Montreal Canadiens and the Buffalo Sabres.

We've got you covered, in terms of the vital info about NHL betting lines, before you make your wager on FanDuel Sportsbook.

Canadiens vs Sabres Game Info

• Montreal Canadiens (28-15-7) vs. Buffalo Sabres (27-17-5)
• Date: Thursday, January 22, 2026
• Time: 7 p.m. ET
• Venue: Bell Centre -- Montréal, Quebec
• Coverage: ESPN+

Canadiens vs Sabres Odds

All NHL odds, betting lines and prop bets are available on FanDuel Sportsbook.

Canadiens vs Sabres Prediction & Pick

All NHL win probability predictions and picks are according to numberFire.

• Prediction: Sabres win (52.8%)

Canadiens vs Sabres Puck Line

• The Sabres are underdogs by 1.5 goals (-245 to cover). And Montreal, the favorite, is +194.

Canadiens vs Sabres Over/Under

• Canadiens versus Sabres on Jan. 22 has an over/under of 6.5 goals, with the over -115 and the under -105.

Canadiens vs Sabres Moneyline

• Montreal is a -126 favorite on the moneyline, while Buffalo is a +105 underdog on the road.

Sign up for FanDuel Sportsbook and FanDuel Daily Fantasy today!