Bulls vs. Cavaliers Prediction, Odds, Picks, Best Bets for Dec. 17

Bulls vs. Cavaliers Game Info

• Date: Wednesday, December 17, 2025
• Time: 8 p.m. ET
• Venue: United Center -- Chicago, Illinois
• Coverage: CHSN and FDSOH

The Chicago Bulls (10-15) are underdogs (by 5 points) to break a four-game home losing streak when they host the Cleveland Cavaliers (15-12) on Wednesday, December 17, 2025 at 8 p.m. ET. The point total in the matchup is set at 240.5.

Bulls vs. Cavaliers Odds & Spread

All NBA betting lines, odds and prop bets are from FanDuel Sportsbook.

Bulls vs. Cavaliers Prediction & Pick

All NBA win probability predictions and picks are according to numberFire.
Prediction: Cavaliers win (66.7%)

Bulls vs. Cavaliers Betting Trends

• The Cavaliers have covered the spread nine times this season (9-18-0).
• Against the spread, the Bulls are 10-14-1 this year.
• This season, 12 of the Cavaliers' games have gone over the point total out of 25 chances.
• Bulls games this year have gone over the point total 52% of the time (13 out of 25 games with a set point total).
• Against the spread, Cleveland has fared worse at home, covering five times in 16 home games, and four times in 11 road games.
• Looking at point totals, the Cavaliers hit the over less often at home, as they've exceeded the total four times in 16 opportunities this season (25%). In away games, they have hit the over eight times in 11 opportunities (72.7%).
• This year, Chicago is 5-6-1 at home against the spread (.417 winning percentage). Away, it is 5-8-0 ATS (.385).
• Bulls games have gone above the over/under 41.7% of the time at home (five of 12), and 61.5% of the time on the road (eight of 13).

Cavaliers Leaders

• Donovan Mitchell averages 30.7 points, 4.7 rebounds and 5.5 assists.
• Jaylon Tyson averages 13.1 points, 5.7 rebounds and 1.9 assists.
• De'Andre Hunter is averaging 15.4 points, 4.3 rebounds and 2.3 assists. At the other end, he averages 0.7 steals and 0.1 blocked shots.
• Jarrett Allen is averaging 14 points, 7.3 boards and 1.8 assists.
• Lonzo Ball is averaging 5.6 points, 4.8 assists and 4.6 rebounds.

Bulls Leaders

• Josh Giddey averages 20.1 points for the Bulls, plus 9.3 boards and 8.8 assists.
• Nikola Vucevic's numbers on the season are 15.6 points, 9.1 rebounds and 3.4 assists per contest. He is making 47.8% of his shots from the field and 37.9% from 3-point range, with an average of 1.8 triples.
• The Bulls are receiving 13.6 points, 5.5 boards and 1.6 assists per game from Matas Buzelis.
• The Bulls get 12.5 points per game from Tre Jones, plus 3.1 rebounds and 4.9 assists.
• Ayo Dosunmu averages 15.2 points, 2.7 rebounds and 3.2 assists. He is sinking 51.9% of his shots from the floor and 47.5% from 3-point range (fifth in NBA), with 1.9 triples per game.

For more NBA betting insights, check out FanDuel Research's NBA home page.

Sign up for FanDuel Sportsbook and FanDuel Daily Fantasy today!

Watch FanDuel TV's NBA show "Run It Back" with Lou Williams, Michelle Beadle, DeMarcus "Boogie" Cousins and Chandler Parsons weekdays at 10am ET on FanDuel TV, the Run It Back YouTube page, or download the podcast here: fanduel.com/research/tv-and-podcast.