Buccaneers vs 49ers Prediction, Odds, Picks, Best Bets for NFL Week 6

The Tampa Bay Buccaneers versus the San Francisco 49ers is on the NFL schedule for Sunday.

We've got you covered, in terms of the most important information about NFL betting lines, before you make your wager on FanDuel Sportsbook.

Buccaneers vs 49ers Prediction & Pick

All NFL win probability predictions and picks are according to numberFire.
Prediction: Buccaneers win (70.1%)

Buccaneers vs 49ers Point Spread

The Buccaneers are 3-point favorites against the 49ers. The Buccaneers are -105 to cover the spread, while the 49ers are -115 to cover as a 3-point underdog.

Buccaneers vs 49ers Over/Under

A combined point total of 47.5 has been set for Buccaneers-49ers on Oct. 12, with the over at -108 and the under at -112.

Buccaneers vs 49ers Moneyline

Tampa Bay is a -154 favorite on the moneyline, while San Francisco is a +130 underdog on the road.

Buccaneers vs 49ers Betting Trends

• Tampa Bay has three wins in five games against the spread this season.
• The Buccaneers don't have a win ATS (0-1) as a 3-point favorite or greater this year.
• This year, three of the Buccaneers' five games have gone over the point total.
• The 49ers are 3-2-0 against the spread this season.
• San Francisco is unbeaten ATS (1-0) as a 3-point underdog or more this season.
• Out of five 49ers games so far this season, three have hit the over.

Check out even more in-depth Buccaneers vs. 49ers analysis on FanDuel Research.

Buccaneers vs 49ers Odds & Spread

• All NFL odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: TB: (-154) | SF: (+130)
• Spread: TB: -3 (-105) | SF: +3 (-115)
• Total: 47.5 -- Over: (-108) | Under: (-112)

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