Brock Purdy Fantasy Football Week 16: Stats and Projections vs. Colts

San Francisco 49ers QB Brock Purdy will take on the 30th-ranked pass defense of the Indianapolis Colts (247.6 yards allowed per game) in Week 16, at 8:15 p.m. ET on Monday.

Is Purdy a DFS option for you this week, as he goes up against the Colts? More stats and info can be found below, so check it out.

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Brock Purdy Week 16 Fantasy Football Projection

• Matchup: San Francisco 49ers at Indianapolis Colts
• Game Date: December 22, 2025
• Game Time: 8:15 p.m.
• Projected Fantasy Points: 18.5
• Projected Passing Yards: 256.26
• Projected Passing TDs: 1.88
• Projected Rushing Yards: 16.59
• Projected Rushing TDs: 0.18

Projections provided by numberFire

Purdy Fantasy Performance

• Purdy is currently the 33rd-ranked fantasy player at his position (122nd overall), posting 104.4 total fantasy points (17.4 per game).
• During his last three games, Purdy has accumulated 656 passing yards (62-of-91) for five passing TDs with three picks, leading to 50.6 fantasy points (16.9 per game) during that period. On the ground, he's contributed 64 yards rushing on 15 carries with one touchdown.
• Purdy has piled up 1,165 passing yards (103-of-155) with 10 TDs and five picks in his last five games, leading to 87.6 fantasy points (17.5 per game) during that stretch. On the ground, he's contributed 70 yards rushing on 18 carries with one touchdown.
• The highlight of Purdy's fantasy season so far was last week against the Tennessee Titans, when he carried seven times for 44 yards on his way to 26.2 fantasy points.
• From a fantasy perspective, Brock Purdy disappointed his fantasy managers against the Carolina Panthers in Week 12, when he managed only 7.3 fantasy points -- 23-of-32 (71.9%), 193 yards, 1 TD, 3 INTs. It was his worst fantasy effort of the year.

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Colts Defensive Performance

• Indianapolis has allowed over 300 yards passing to four players this year.
• A total of 10 players have thrown for at least one TD versus the Colts this year.
• Indianapolis has allowed five players to throw for at least two touchdowns in a game this season.
• The Colts have allowed three players to throw for at least three TDs in a game this season.
• Indianapolis has allowed more than 100 yards receiving to six players this year.
• The Colts have given up a touchdown catch by 18 players this season.
• Indianapolis has not allowed more than one touchdown catch to an opposing player this season.
• One player has collected more than 100 yards rushing in a game against the Colts this year.
• Indianapolis has allowed at least one rushing TD to 10 players this season.
• A total of Three players have run for more than one touchdown against the Colts this year.

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