Brewers vs Pirates Prediction, Odds, Moneyline, Spread & Over/Under for Sept. 5

Odds updated as of 2:12 a.m.

In MLB action on Friday, the Milwaukee Brewers face the Pittsburgh Pirates.

Here's what you need to know before checking out today's MLB odds and spreads on FanDuel Sportsbook.

Brewers vs Pirates Game Info

• Milwaukee Brewers (86-55) vs. Pittsburgh Pirates (64-77)
• Date: Friday, September 5, 2025
• Time: 6:40 p.m. ET
• Venue: PNC Park -- Pittsburgh, Pennsylvania
• Coverage: Apple TV+

Brewers vs Pirates Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: MIL: (-148) | PIT: (+126)
• Spread: MIL: -1.5 (+105) | PIT: +1.5 (-126)
• Total: 8.5 -- Over: (-115) | Under: (-105)

Brewers vs Pirates Probable Starting Pitchers

Probable Pitchers: Quinn Priester (Brewers) - 11-2, 3.28 ERA vs Johan Oviedo (Pirates) - 2-0, 3.60 ERA

The Brewers will look to Quinn Priester (11-2) against the Pirates and Johan Oviedo (2-0). Priester's team is 12-8-0 against the spread this season in his starts. Priester's team has been victorious in 77.8% of the games he's started as the moneyline favorite with a record of 7-2. The Pirates covered in each of Oviedo's four starts that had a set spread. The Pirates have a 3-1 record in Oviedo's four starts this season when they were the moneyline underdog.

Brewers vs Pirates Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Brewers win (60.3%)

Brewers vs Pirates Moneyline

• Looking at the moneyline for Brewers-Pirates, Milwaukee is the favorite at -148, and Pittsburgh is +126 playing at home.

Brewers vs Pirates Spread

• The Brewers are favored by 1.5 runs on the road versus the Pirates. The Brewers are +105 to cover the spread, while the Pirates are -126.

Brewers vs Pirates Over/Under

• Brewers versus Pirates on Sept. 5 has an over/under of 8.5 runs, with the odds on the over -115 and the under set at -105.

Bet on Milwaukee Brewers vs. Pittsburgh Pirates on FanDuel today!

Brewers vs Pirates Betting Trends

• The Brewers have been favorites in 77 games this season and have come away with the win 50 times (64.9%) in those contests.
• This year Milwaukee has won 24 of 33 games when listed as at least -148 on the moneyline.
• The Brewers' games have gone over the total in 69 of their 138 opportunities.
• The Brewers have posted a record of 78-60-0 against the spread this season.
• The Pirates have a 41-52 record in games they were the underdog on the moneyline (winning 44.1% of those games).
• In games it has played as a moneyline underdog with odds of +126 or longer, Pittsburgh has an 18-32 record (winning only 36% of its games).
• The Pirates have combined with opponents to go over the total 53 times this season for a 53-74-6 record against the over/under.
• The Pirates have collected a 74-59-0 record against the spread this season.

Brewers Player Leaders

• Brice Turang leads Milwaukee with a slugging percentage of .449, fueled by 44 extra-base hits. He has a .291 batting average and an on-base percentage of .358.
• He is 15th in batting average, 25th in on-base percentage, and 62nd in slugging among qualified hitters in MLB.
• William Contreras is hitting .261 with 26 doubles, 17 home runs and 77 walks. He's slugging .411 with an on-base percentage of .357.
• Among qualifying hitters, he ranks 73rd in batting average, 28th in on-base percentage and 91st in slugging percentage.
• Contreras has picked up at least one hit in four straight games. During his last five outings he is batting .300 with a double, a home run, two walks and three RBIs.
• Christian Yelich has collected 134 base hits, an OBP of .350 and a slugging percentage of .464 this season.
• Jackson Chourio leads Milwaukee in total hits (129) this season while batting .279 with 53 extra-base hits.

Pirates Player Leaders

• Bryan Reynolds has a team-best slugging percentage (.411) and paces the Pirates in hits (127). He's batting .246 and with an on-base percentage of .313.
• Including all qualified hitters, he ranks 108th in batting average, while his on-base percentage ranks 113th and he is 91st in slugging.
• Oneil Cruz is batting .202 with 17 doubles, two triples, 19 home runs and 59 walks. He's slugging .389 with an on-base percentage of .304.
• He is currently 152nd in batting average, 126th in on-base percentage and 122nd in slugging percentage among all qualified hitters.
• Andrew McCutchen has racked up a team-high .342 on-base percentage.
• Tommy Pham is batting .264 with 16 doubles, a triple, eight home runs and 39 walks.

Brewers vs Pirates Head to Head

• 8/13/2025: 12-5 MIL (Favorite: Brewers, Spread: -1.5, Total: 7.5, Favorite Moneyline: -240, Underdog Moneyline: +198)
• 8/12/2025: 14-0 MIL (Favorite: Brewers, Spread: -1.5, Total: 6.5, Favorite Moneyline: -134, Underdog Moneyline: +114)
• 8/11/2025: 7-1 MIL (Favorite: Brewers, Spread: -1.5, Total: 9, Favorite Moneyline: -196, Underdog Moneyline: +164)
• 6/25/2025: 4-2 MIL (Favorite: Brewers, Spread: -1.5, Total: 6.5, Favorite Moneyline: -108, Underdog Moneyline: -108)
• 6/24/2025: 9-3 MIL (Favorite: Brewers, Spread: -1.5, Total: 7.5, Favorite Moneyline: -210, Underdog Moneyline: +176)
• 6/23/2025: 5-4 PIT (Favorite: Brewers, Spread: -1.5, Total: 8.5, Favorite Moneyline: -180, Underdog Moneyline: +152)
• 5/25/2025: 6-5 MIL (Favorite: Brewers, Spread: -1.5, Total: 8, Favorite Moneyline: -154, Underdog Moneyline: +130)
• 5/24/2025: 2-1 PIT (Favorite: Brewers, Spread: -1.5, Total: 8.5, Favorite Moneyline: -110, Underdog Moneyline: -106)
• 5/23/2025: 6-5 PIT (Favorite: Pirates, Spread: -1.5, Total: 7, Favorite Moneyline: -124, Underdog Moneyline: +106)
• 5/22/2025: 8-5 MIL (Favorite: Brewers, Spread: -1.5, Total: 9, Favorite Moneyline: -112, Underdog Moneyline: -104)

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