Best College Football Games Week 15: Predictions, Odds, Picks, Best Bets

Top-25 teams will hit the field across six games on the Week 15 college football slate. That includes the No. 2 Indiana Hoosiers playing the No. 1 Ohio State Buckeyes at Lucas Oil Stadium.

Searching for an edge in college football? We dissect the betting odds for all the important games below.

For additional insights, check out the latest college football betting picks from FanDuel Research's staff of writers.

James Madison vs. Troy

• Matchup: Troy Trojans at No. 19 James Madison Dukes
• Projected Favorite: James Madison (97.43% win probability)
• Spread: James Madison (-23.5)
• Total: 46.5
• Time: 7 p.m. ET
• Date: Dec. 5
• TV Channel: ESPN

Bet on James Madison vs. Troy with FanDuel Sportsbook.

Tulane vs. North Texas

• Matchup: No. 20 North Texas Mean Green at No. 21 Tulane Green Wave
• Projected Favorite: North Texas (66.33% win probability)
• Spread: North Texas (-2.5)
• Total: 66.5
• Time: 8 p.m. ET
• Date: Dec. 5
• TV Channel: ABC

Bet on Tulane vs. North Texas with FanDuel Sportsbook.

Texas Tech vs. BYU

• Matchup: No. 11 BYU Cougars vs. No. 5 Texas Tech Red Raiders
• Projected Favorite: Texas Tech (77.28% win probability)
• Spread: Texas Tech (-12.5)
• Total: 49.5
• Time: 12 p.m. ET
• Date: Dec. 6
• TV Channel: ABC

Bet on Texas Tech vs. BYU with FanDuel Sportsbook.

Alabama vs. Georgia

• Matchup: No. 3 Georgia Bulldogs vs. No. 10 Alabama Crimson Tide
• Projected Favorite: Georgia (50.60% win probability)
• Spread: Georgia (-2.5)
• Total: 48.5
• Time: 4 p.m. ET
• Date: Dec. 6
• TV Channel: ABC

Bet on Alabama vs. Georgia with FanDuel Sportsbook.

Virginia vs. Duke

• Matchup: Duke Blue Devils vs. No. 16 Virginia Cavaliers
• Projected Favorite: Virginia (66.23% win probability)
• Spread: Virginia (-3.5)
• Total: 57.5
• Time: 8 p.m. ET
• Date: Dec. 6
• TV Channel: ABC

Bet on Virginia vs. Duke with FanDuel Sportsbook.

Ohio State vs. Indiana

• Matchup: No. 2 Indiana Hoosiers vs. No. 1 Ohio State Buckeyes
• Projected Favorite: Ohio State (57.98% win probability)
• Spread: Ohio State (-4.5)
• Total: 46.5
• Time: 8 p.m. ET
• Date: Dec. 6
• TV Channel: FOX

Bet on Ohio State vs. Indiana with FanDuel Sportsbook.

Matchup favorites and win projections are provided by numberFire.

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