Astros vs Orioles Prediction, Odds, Moneyline, Spread & Over/Under for Aug. 16

Odds updated as of 11:12 a.m.

On Saturday in MLB, the Houston Astros are playing the Baltimore Orioles.

Before checking out the MLB betting lines on FanDuel Sportsbook, we've got you covered, in terms of the most important information about this game.

Astros vs Orioles Game Info

• Houston Astros (68-54) vs. Baltimore Orioles (56-66)
• Date: Saturday, August 16, 2025
• Time: 7:10 p.m. ET
• Venue: Daikin Park -- Houston, Texas
• Coverage: SCHN and MASN2

Astros vs Orioles Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: HOU: (-220) | BAL: (+184)
• Spread: HOU: -1.5 (-102) | BAL: +1.5 (-118)
• Total: 7.5 -- Over: (-112) | Under: (-108)

Astros vs Orioles Probable Starting Pitchers

Probable Pitchers: Jason Alexander (Astros) - 3-1, 5.02 ERA vs Rico Garcia (Orioles) - 0-0, 3.71 ERA

The probable pitchers are Jason Alexander (3-1) for the Astros and Rico Garcia for the Orioles. Alexander and his team are 4-1-0 ATS this season when he starts. Alexander's team has been victorious in 66.7% of the games he's started as the moneyline favorite with a record of 2-1. Garcia's team was never a moneyline underdog a season ago in games he pitched.

Astros vs Orioles Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Astros win (55.9%)

Astros vs Orioles Moneyline

• Baltimore is the underdog, +184 on the moneyline, while Houston is a -220 favorite at home.

Astros vs Orioles Spread

• The Astros are hosting the Orioles and are favored by 1.5 runs (-102 to cover) on the runline. Baltimore is -118 to cover.

Astros vs Orioles Over/Under

• Astros versus Orioles on Aug. 16 has an over/under of 7.5 runs, with the odds on the over -112 and the under set at -108.

Bet on Houston Astros vs. Baltimore Orioles on FanDuel today!

Astros vs Orioles Betting Trends

• The Astros have been favorites in 79 games this season and have come away with the win 42 times (53.2%) in those contests.
• This year Houston has won four of seven games when listed as at least -220 on the moneyline.
• Contests with the Astros have gone over the total set by bookmakers in 53 of 121 chances this season.
• The Astros are 61-60-0 against the spread in their 121 games that had a posted line this season.
• The Orioles have been the underdog on the moneyline 63 total times this season. They've gone 29-34 in those games.
• Baltimore has gone 2-1 when playing as a moneyline underdog with odds of +184 or longer (66.7%).
• In the 119 games bookmakers have set an over/under for the Orioles, they have combined with opponents to go over the total 50 times (50-65-4).
• The Orioles have collected a 54-65-0 record ATS this season (covering 45.4% of the time).

Astros Player Leaders

• Jose Altuve has an OPS of .810, fueled by an OBP of .345 and a team-best slugging percentage of .465 this season. He has a .281 batting average.
• He ranks 26th in batting average, 52nd in on-base percentage, and 45th in slugging among qualified batters in MLB.
• Jeremy Pena leads the Astros in OBP (.373) and total hits (115) this season. He's batting .318 while slugging .492.
• Among qualifying batters, he is second in batting average, 13th in on-base percentage and 27th in slugging percentage.
• Pena brings a three-game streak with at least one hit into this one. During his last five outings he is batting .273 with two home runs, a walk and two RBIs.
• Yainer Diaz is batting .252 with a .420 slugging percentage and 53 RBI this year.
• Christian Walker has 16 home runs, 65 RBI and a batting average of .232 this season.

Orioles Player Leaders

• Gunnar Henderson has accumulated an on-base percentage of .351, a slugging percentage of .466, and has 122 hits, all club-highs for the Orioles (while batting .283).
• Including all qualifying hitters in MLB, he ranks 24th in batting average, 42nd in on-base percentage and 42nd in slugging percentage.
• Henderson enters this game on an eight-game hitting streak. During his last 10 outings he is batting .257 with four doubles, a home run, two walks and six RBIs.
• Jackson Holliday has 16 doubles, two triples, 14 home runs and 29 walks while batting .248. He's slugging .385 with an on-base percentage of .300.
• Including all qualifying hitters, his batting average places him 103rd, his on-base percentage is 133rd, and he is 129th in slugging.
• Adley Rutschman is batting .232 with 16 doubles, a triple, nine home runs and 37 walks.
• Jordan Westburg has nine doubles, a triple, 14 home runs and 15 walks while batting .268.

Astros vs Orioles Head to Head

• 8/15/2025: 7-0 BAL (Favorite: Astros, Spread: -1.5, Total: 7.5, Favorite Moneyline: -220, Underdog Moneyline: +184)
• 8/25/2024: 6-3 HOU (Favorite: Orioles, Spread: -1.5, Total: 8, Favorite Moneyline: -110, Underdog Moneyline: -106)
• 8/24/2024: 3-2 BAL (Favorite: Orioles, Spread: -1.5, Total: 8.5, Favorite Moneyline: -110, Underdog Moneyline: -106)
• 8/23/2024: 7-5 BAL (Favorite: Astros, Spread: -1.5, Total: 8, Favorite Moneyline: -120, Underdog Moneyline: +102)
• 8/22/2024: 6-0 HOU (Favorite: Orioles, Spread: -1.5, Total: 7.5, Favorite Moneyline: -152, Underdog Moneyline: +128)
• 6/23/2024: 8-1 HOU (Favorite: Astros, Spread: -1.5, Total: 8.5, Favorite Moneyline: -108, Underdog Moneyline: -108)
• 6/22/2024: 5-1 HOU (Favorite: Orioles, Spread: -1.5, Total: 7.5, Favorite Moneyline: -146, Underdog Moneyline: +124)
• 6/21/2024: 14-11 HOU (Favorite: Orioles, Spread: -1.5, Total: 8.5, Favorite Moneyline: -154, Underdog Moneyline: +130)
• 9/20/2023: 2-1 HOU (Favorite: Orioles, Spread: -1.5, Total: 9, Favorite Moneyline: -120, Underdog Moneyline: +102)
• 9/19/2023: 9-5 BAL (Favorite: Astros, Spread: -1.5, Total: 9, Favorite Moneyline: -184, Underdog Moneyline: +154)

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