Astros vs Cubs Prediction, Odds, Moneyline, Spread & Over/Under for June 29

Odds updated as of 2:11 p.m.

The Houston Astros are among the MLB teams busy on Sunday, versus the Chicago Cubs.

Here's everything you need to know before checking out today's MLB odds and spreads on FanDuel Sportsbook.

Astros vs Cubs Game Info

• Houston Astros (49-34) vs. Chicago Cubs (49-34)
• Date: Sunday, June 29, 2025
• Time: 2:10 p.m. ET
• Venue: Daikin Park -- Houston, Texas
• Coverage: SCHN

Astros vs Cubs Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: HOU: (-132) | CHC: (+112)
• Spread: HOU: -1.5 (+158) | CHC: +1.5 (-192)
• Total: 7.5 -- Over: (-118) | Under: (-104)

Astros vs Cubs Probable Starting Pitchers

Probable Pitchers: Framber Valdez (Astros) - 8-4, 2.88 ERA vs Jameson Taillon (Cubs) - 7-5, 4.47 ERA

The Astros will give the nod to Framber Valdez (8-4, 2.88 ERA), who is eyeing win No. 9 on the season, and the Cubs will counter with Jameson Taillon (7-5, 4.47 ERA). Valdez's team is 6-9-0 against the spread in his starts this season. When Valdez starts a game and his team is the favorite on the moneyline, they have a record of 8-5. The Cubs have a 7-8-0 record against the spread in Taillon's starts. The Cubs are 1-3 in Taillon's four starts this season that they were the underdog on the moneyline.

Astros vs Cubs Moneyline

• The Astros vs Cubs moneyline has Houston as a -132 favorite, while Chicago is a +112 underdog on the road.

Astros vs Cubs Spread

• The Cubs are +1.5 on the spread (-192 to cover), and Houston is +158 to cover the runline.

Astros vs Cubs Over/Under

• A combined run total of 7.5 has been set for Astros-Cubs on June 29, with the over at -118 and the under at -104.

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Astros vs Cubs Betting Trends

• The Astros have been victorious in 34, or 59.6%, of the 57 contests they have been chosen as favorites in this season.
• This season Houston has been victorious 21 times in 31 chances when named as a favorite of at least -132 on the moneyline.
• Contests with the Astros have gone over the total set by bookmakers in 33 of 82 chances this season.
• The Astros have posted a record of 42-40-0 against the spread this season.
• The Cubs have won 38.5% of the games this season they were the moneyline underdog (10-16).
• Chicago has gone 3-7 when playing as a moneyline underdog with odds of +112 or longer (30%).
• The Cubs have played in 81 games with a set over/under, and have combined with opponents to go over the total 44 times (44-33-4).
• The Cubs have a 41-40-0 record ATS this season (covering 50.6% of the time).

Astros Player Leaders

• Jeremy Pena leads Houston in OBP (.378), slugging percentage (.489) and total hits (102) this season. He has a .322 batting average.
• Among qualifying batters in MLB, his batting average ranks fourth, his on-base percentage ranks 19th, and he is 29th in slugging.
• Isaac Paredes is hitting .254 with 10 doubles, a triple, 17 home runs and 42 walks. He's slugging .471 with an on-base percentage of .360.
• Among all qualified, he is 89th in batting average, 34th in on-base percentage and 47th in slugging percentage.
• Paredes heads into this matchup looking to extend his two-game hit streak. In his last five games he is hitting .222 with a home run, a walk and an RBI.
• Jose Altuve has collected 80 base hits, an OBP of .320 and a slugging percentage of .410 this season.
• Jake Meyers has three home runs, 20 RBI and a batting average of .307 this season.
• Meyers heads into this game on a four-game hitting streak. In his last five games he is hitting .250 with a walk.

Cubs Player Leaders

• Kyle Tucker has an on-base percentage of .396 and a slugging percentage of .537. Both lead the Cubs. He's batting .291.
• Including all qualified hitters in the majors, he is 23rd in batting average, fourth in on-base percentage and 11th in slugging percentage.
• Pete Crow-Armstrong is hitting .266 with 20 doubles, three triples, 21 home runs and 15 walks. He's slugging .544 with an on-base percentage of .302.
• His batting average ranks 62nd among all qualified players, his on-base percentage is 124th, and he is 10th in slugging.
• Seiya Suzuki has racked up 83 hits, a team-high for the Cubs.
• Nico Hoerner is batting .294 with 17 doubles, a triple, three home runs and 17 walks.

Astros vs Cubs Head to Head

• 6/28/2025: 12-3 CHC (Favorite: Astros, Spread: -1.5, Total: 8.5, Favorite Moneyline: -112, Underdog Moneyline: -104)
• 6/27/2025: 7-4 HOU (Favorite: Astros, Spread: -1.5, Total: 8, Favorite Moneyline: -118, Underdog Moneyline: -100)
• 4/25/2024: 3-1 CHC (Favorite: Astros, Spread: -1.5, Total: 7.5, Favorite Moneyline: -144, Underdog Moneyline: +122)
• 4/24/2024: 4-3 CHC (Favorite: Astros, Spread: -1.5, Total: 7.5, Favorite Moneyline: -110, Underdog Moneyline: -106)
• 4/23/2024: 7-2 CHC (Favorite: Astros, Spread: -1.5, Total: 10, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 5/17/2023: 7-6 HOU (Favorite: Astros, Spread: -1.5, Total: 8.5, Favorite Moneyline: -172, Underdog Moneyline: +144)
• 5/16/2023: 7-3 HOU (Favorite: Astros, Spread: -1.5, Total: 7.5, Favorite Moneyline: -178, Underdog Moneyline: +150)
• 5/15/2023: 6-4 HOU (Favorite: Astros, Spread: -1.5, Total: 7.5, Favorite Moneyline: -196, Underdog Moneyline: +164)

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