Alabama vs Oklahoma Prediction, Odds, Picks, Best Bets for Week 12 2025

College football's Saturday slate includes the Alabama Crimson Tide taking on the Oklahoma Sooners.

Before you make your wager on FanDuel Sportsbook, we've got you covered, in terms of the vital info about today's NCAA football betting odds.

Alabama vs Oklahoma Odds & Spread

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• All college football odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: Alabama: (-225) | Oklahoma: (+188)
• Spread: Alabama: -5.5 (-122) | Oklahoma: +5.5 (100)
• Total: 45.5 -- Over: (-112) | Under: (-108)

Alabama vs Oklahoma Betting Trends

• Against the spread, Alabama is 6-3-0 this year.
• As 5.5-point favorites or more, Alabama is 5-2 against the spread.
• Alabama has played nine games this season, and four of them have gone over the total.
• Oklahoma has beaten the spread five times in nine games.
• Oklahoma has played two games (out of nine) which finished over the total this season.

Alabama vs Oklahoma Prediction & Pick

All college football win probability predictions and picks are according to numberFire.
Prediction: Crimson Tide win (72.3%)

Alabama vs Oklahoma Point Spread

Alabama is favored by 5.5 points (-122 to cover) in this matchup. Oklahoma, the underdog, is +100.

Alabama vs Oklahoma Over/Under

An over/under of 45.5 has been set for Alabama-Oklahoma on Nov. 15, with the over being -112 and the under -108.

Alabama vs Oklahoma Moneyline

Alabama is a -225 favorite on the moneyline, while Oklahoma is a +188 underdog.

Alabama vs. Oklahoma Points Insights

Alabama vs. Oklahoma Game Info

• Game day: Saturday, November 15, 2025
• Game time: 3:30 p.m. ET
• TV channel: ABC
• Location: Tuscaloosa, Alabama
• Stadium: Bryant-Denny Stadium

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Check out even more in-depth Alabama vs. Oklahoma analysis on FanDuel Research.