49ers vs Saints Prediction, Odds, Picks, Best Bets for NFL Week 2

In NFL action on Sunday, the San Francisco 49ers face the New Orleans Saints.

All the info you need is below, in order to make a smart bet on this game at FanDuel Sportsbook.

49ers vs Saints Prediction & Pick

All NFL win probability predictions and picks are according to numberFire.
Prediction: 49ers win (61.4%)

49ers vs Saints Point Spread

The 49ers are 4.5-point favorites against the Saints. The 49ers are -115 to cover the spread, while the Saints are -105 to cover as a 4.5-point underdog.

49ers vs Saints Over/Under

A total of 42.5 points has been set for the 49ers-Saints matchup on Sept. 14, with the over available at -115 and the under at -105.

49ers vs Saints Moneyline

New Orleans is a +194 underdog on the moneyline, while San Francisco is a -235 favorite at home.

49ers vs Saints Betting Trends

• The 49ers had five wins in 17 games against the spread last season.
• As a 4.5-point favorite or more, the 49ers had two wins ATS (2-5) last season.
• In 17 San Francisco games last season, 11 went over the total.
• The Saints' record against the spread last season was 7-10-0.
• New Orleans went 3-3 as underdogs of 4.5 points or greater last season.
• The Saints had eight of their 17 games hit the over last season.

Check out even more in-depth 49ers vs. Saints analysis on FanDuel Research.

49ers vs Saints Odds & Spread

• All NFL odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: SF: (-235) | NO: (+194)
• Spread: SF: -4.5 (-115) | NO: +4.5 (-105)
• Total: 42.5 -- Over: (-115) | Under: (-105)

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