49ers vs Cardinals Prediction, Odds, Picks, Best Bets for NFL Week 11

NFL action on Sunday includes the San Francisco 49ers facing the Arizona Cardinals.
Before you place your bet on this game at FanDuel Sportsbook, here are the NFL moneyline insights you need to know.
49ers vs Cardinals Prediction & Pick
All NFL win probability predictions and picks are according to numberFire.
Prediction: Cardinals win (52.1%)
49ers vs Cardinals Point Spread
The 49ers are 3-point favorites against the Cardinals. The 49ers are -108 to cover the spread, while the Cardinals are -112 to cover as a 3-point underdog.
49ers vs Cardinals Over/Under
The 49ers-Cardinals game on Nov. 16 has been given an over/under of 47.5 points. The over is -115 and the under is -105.
49ers vs Cardinals Moneyline
Looking at the moneyline for 49ers-Cardinals, San Francisco is the favorite at -164, and Arizona is +138 playing at home.
49ers vs Cardinals Betting Trends
- San Francisco has five wins in 10 games against the spread this season.
- The 49ers have one win ATS (1-1) as a 3-point favorite or greater this season.
- Out of 10 49ers games so far this season, six have gone over the total.
- The Cardinals are 5-4-0 against the spread this year.
- As 3-point underdogs or greater, Arizona is 3-1 against the spread.
- There have been five Cardinals games (out of nine) that hit the over this season.
Check out even more in-depth 49ers vs. Cardinals analysis on FanDuel Research.
49ers vs Cardinals Odds & Spread
- All NFL odds, betting lines and prop bets are available on FanDuel Sportsbook.
- Moneyline: SF: (-164) | ARI: (+138)
- Spread: SF: -3 (-108) | ARI: +3 (-112)
- Total: 47.5 -- Over: (-115) | Under: (-105)
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