49ers vs Browns Prediction, Odds, Picks, Best Bets for NFL Week 13

Sunday's slate in the NFL includes a matchup between the San Francisco 49ers and the Cleveland Browns.

All the info you need is below, in order to make a smart bet on this matchup at FanDuel Sportsbook.

49ers vs Browns Prediction & Pick

All NFL win probability predictions and picks are according to numberFire.
Prediction: 49ers win (62.4%)

49ers vs Browns Point Spread

The 49ers are 5.5-point favorites against the Browns. The 49ers are -110 to cover the spread, while the Browns are -110 to cover as a 5.5-point underdog.

49ers vs Browns Over/Under

49ers versus Browns, on Nov. 30, has an over/under of 35.5, with the over being -110 and the under -110.

49ers vs Browns Moneyline

Cleveland is a +220 underdog on the moneyline, while San Francisco is a -270 favorite at home.

49ers vs Browns Betting Trends

• San Francisco is 7-5-0 against the spread this season.
• The 49ers are unbeaten ATS (1-0) as a 5.5-point favorite or greater this season.
• Out of 12 49ers games so far this year, seven have gone over the total.
• The Browns have five wins in 11 contests against the spread this year.
• Cleveland has two wins ATS (2-4) as a 5.5-point underdog or greater this season.
• The Browns have seen six of their 11 games go over the point total.

Check out even more in-depth 49ers vs. Browns analysis on FanDuel Research.

49ers vs Browns Odds & Spread

• All NFL odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: SF: (-270) | CLE: (+220)
• Spread: SF: -5.5 (-110) | CLE: +5.5 (-110)
• Total: 35.5 -- Over: (-110) | Under: (-110)

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