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NFL

2025 San Francisco 49ers Schedule, Results, TV Channel

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2025 San Francisco 49ers Schedule, Results, TV Channel

As part of their 2025 NFL schedule, the San Francisco 49ers have what should be a tough matchup against the Tampa Bay Buccaneers on Oct. 12. You can check out the 49ers' complete schedule below. Wanting additional details on the San Francisco 49ers' 2025 results and NFL schedule? We've got you covered in the article below.

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49ers' 2025 Schedule

Date/Time
Opponent
Odds/Score
Location
TV Channel
Sunday, Sept. 7 at 4:05 p.m. ET@ Seahawks49ers (-1.5) | O/U: 45.5Lumen Field, Seattle, WashingtonFOX
Sunday, Sept. 14 at 1 p.m. ET@ Saints-Caesars Superdome, New Orleans, LouisianaFOX
Sunday, Sept. 21 at 4:25 p.m. ETCardinals-Levi's Stadium, Santa Clara, CaliforniaFOX
Sunday, Sept. 28 at 4:05 p.m. ETJaguars-Levi's Stadium, Santa Clara, CaliforniaFOX
Thursday, Oct. 2 at 8:15 p.m. ET@ Rams-SoFi Stadium, Inglewood, CaliforniaAmazon Prime Video
Sunday, Oct. 12 at 1 p.m. ET@ Buccaneers-Raymond James Stadium, Tampa, FloridaCBS
Sunday, Oct. 19 at 8:20 p.m. ETFalcons-Levi's Stadium, Santa Clara, CaliforniaNBC

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